葛晓春

基本信息

职称:教授
电话:021-31246
642
邮箱:xcge@fudan.edu.cn
地址:复旦大学生命科学学院D412

 

个人简介

女,教授,博士生导师。复旦大学学士、硕士和博士学位,1991年起于复旦大学任教;2003~2005年在美国Donald Danforth Plant Science Center进行博士后研究。2011年任博士生导师,2013年起任复旦大学教授,先后承担973、转基因专项、国家自然科学基金委、上海市科委等多个项目的研究任务,担任Scientific Reports杂志编辑等职。

 

主要研究方向 (Research Interests)

干旱、盐胁迫等逆境给植物的生长发育以及粮食作物产量造成了重大影响,本实验室主要利用拟南芥和水稻作为研究对象,研究胁迫响应相关蛋白质的功能及环境因素胁迫下的植物生长发育变化。近几年来,我们以水稻作为研究对象研究了多个调控植物干旱胁迫响应的转录因子、信号转导蛋白、酶等蛋白质的功能,阐明了这些基因对植物生长发育和干旱耐受性的影响;以拟南芥为研究对象,研究了DNA损伤响应中一些调控蛋白质的功能,并以此为基础,发掘和研究植物中新的与损伤响应相关蛋白质的分子机制。

 

获奖情况 (Awards)

2007年 入选浦江人才计划

 

代表性成果

1. Gu Z, Pan W, Chen W, Ge X*. (2019) New perspectives on the plant PARP family: Arabidopsis PARP3 is inactive, and PARP1 exhibits predominant poly (ADP-ribose) polymerase activity in response to DNA damage. BMC plant Biol., 19: 364

2. Yao L, Cheng X, Gu Z, Huang W, Li S, Wang L, Wang Y, Xu P, Ma H, Ge X*. (2018) AWPM-19 family protein OsPM1 mediates abscisic acid influx and drought response in rice. Plant Cell, 30: 1258-1276

3. Jin Y, Pan W, Zheng X, Cheng X, Liu M, Ma H*, Ge X*. (2018) OsERF101, an ERF family transcription factor, regulates drought stress response in reproductive tissues. Plant Mol. Biol., 98:51-65

4. Liu C, Wu Q, Liu W, Gu Z, Wang W, Xu P, Ma H, Ge X*. (2017) Poly(ADP-ribose) polymerases regulate root cell division and inhibition of PARP activities enhances root development. J. Integr. Plant Biol., 59(7): 459-474   

5. Guo C, Yao L, You C, Wang S, Cui J, Ge X*, Ma H*. (2016) MID1 plays an important role in response to drought stress during reproductive development. Plant J., 88(2): 280-293.

6. Zhang H, Gu Z, Wu Q, Yang L, Liu C, Ma H, Xia Y, Ge X*. (2015) Arabidopsis PARG1 is the key factor promoting cell survival among the enzymes regulating post-translational poly(ADP-ribosyl)ation. Sci. Rep., 5:15892. doi: 10.1038/srep15892.   .

7. Jin Y, Yang H, Wei Z, Ma H, Ge X*. (2013) Rice male development under drought stress: phenotypic changes and stage-dependent transcriptomic reprogramming. Mol. Plant, 6: 1630-45.     

8. Guo C, Ge X*, Ma H*. (2013) The rice OsDIL gene plays a role in drought tolerance at vegetative and reproductive stages. Plant Mol. Biol., 82:239-253

9. Wang H, Lu Y, Liu P, Wen W, Zhang J, Ge X*, Xia Y*. (2013) The ammonium/ nitrate ratio is an input signal in the temperature-modulated, SNC1- mediated and EDS1-dependent autoimmunity of nudt6-2nudt7. Plant J., 73: 262-275.

10. Wang H, Wang S, Lu Y, Alvarez S, Hicks L, Ge X*, Xia Y*. (2012) Proteomic Analysis of Early-Responsive Redox-Sensitive Proteins in Arabidopsis. J. Proteom Res., 11: 412-424

11. Wang H, Liang Q, Cao K, Ge X*. (2011) Endogenous protein mono-ADP-ribosylation in Arabidopsis thaliana. Planta, 233:1287-1292

12. Wu Y, He Y, Ge X*. (2011) Functional characterization of the recombinant antimicrobial peptide Trx-Ace-AMP1 and its application on the control of tomato early blight disease. Appl. Microbiol. Biotechnol., 90:1303-1310

13. Ge X, Chang F, Ma H. (2010) Signaling and transcriptional control of reproductive development in Arabidopsis. Curr. Biol., 20: 988-997

14. Ge X, Li G, Wang S, Zhu H, Zhu T, Wang X, Xia Y*. (2007) AtNUDT7, a negative regulator of basal immunity in arabidopsis, modulates two distinct defense response pathways and is involved in maintaining redox homeostasis. Plant Physiol., 145: 204-215

15. Ge X, Dietrich C, Matsuno M, Li G, Berg H, Xia Y*. (2005) An Arabidopsis aspartic protease functions as an anti-cell-death component in reproduction and embryogenesis. EMBO Rep., 6(3):283-288.

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