郭苏

基本信息

职称:教授
电话:021-516
30577
邮箱:suguo@fudan.edu.cn
地址:复旦大学生命科学学院 E201-4室

 

个人简介

1970年生, 特聘讲座教授(复旦大学)。1991年复旦大学遗传系本科毕业, 96年获得美国康奈尔大学博士学位,1996-1997年在哈佛大学医学院做医学研究员,1997-2000 年在美国基因泰克公司从事博士后工作。2001年起任加州大学旧金山分校生物工程与治疗科学系助理教授,副教授,教授。

 

主要研究方向 (Research Interests)

体内干细包形态与功能和癌症及器官再生的相关性;神经网络的发育与功能及行为调控

 

获奖情况 (Awards)

康奈尔大学研究生院刘氏家族纪念奖(Liu Memorial Award, Cornell Graduate School); 安玛西亚青年生物科学家奖, 决赛入选者(Finalist, Amersham Pharmacia Biotech and Science Prize for Young Scientist); 勃罗韦尔康奖(Burroughs Wellcome Award); 塞尔学者奖 (Searle Scholar Award);帕卡德科学与工程奖 (Packard Fellow of Science & Engineering Award); 加大Sandler 奖(UCSF Sandler Award);加大Byers 奖 (UCSF Byers Award)

 

代表性成果

Dong, Z., Peng, J., and Guo, S. * (2013) Stable gene silencing in zebrafish with spatiotemporally targetable RNA interference. Genetics 193: 1065-71.

Dong, Z., Yang, N., Yeo, S., Chitnis, A., and Guo, S. * (2012) Intra-lineage Directional Notch Signaling Regulates Self-renewal and Differentiation of Asymmetrically Dividing Radial Glia. Neuron 74: 65-78

Lau, B., Mathur, P., Gould, G., and Guo, S. * (2011) Identification of a brain center whose activity discriminates a choice behavior in zebrafish. Proc. Natl. Acad. Sci. 108: 2581-6. PMCID: PMC3038752

Peng, J., Wagle, M., Mueller, T., Mathur, P., Lockwood, B.L., Bretaud, S., Guo S. * (2009) Ethanol-modulated camouflage response screen in zebrafish uncovers a novel role for cAMP and extracellular signal-regulated kinase signaling in behavioral sensitivity to ethanol. J Neurosci. 29(26):8408-18. PMCID: PMC2722107

Jeong, J., Einhorn, Z., Mathur, P., Chen, L., Lee, S., Kawakami, K., and Guo, S. * (2007) Patterning the zebrafish diencephalon by the conserved zinc finger protein Fezl. Development 134, 127-136.

Guo, S., Y. Yamaguchi, S. Schilbach, T. Wada, A. Goddard, J. Lee, D. French, H. Handa, and A. Rosenthal (2000). A regulator of transcriptional elongation, which is required for vertebrate neuronal development. Nature 408, 366-369.

Guo, S., and K. J. Kemphues. (1996). A nonmuscle myosin required for embryonic polarity in Caenorhabditis elegans. Nature 382: 455-458.

Guo, S., and K. J. Kemphues. (1995). par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative serine/threonine kinase that is asymmetrically distributed. Cell 81: 611-620.

 

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