胡长龙

基本信息

职称:研究员
电话:021-51630652
邮箱:clhu@fudan.edu.cn
地址:复旦大学生命科学学院 C209室

 

个人简介

男,博士,研究员,博士生导师。

2005年毕业于复旦大学生命科学学院,获理学博士学位;

Ph.D. from Fudan University (2005);

2005年7月至2009年12月,在美国弗吉尼亚大学从事博士后研究;

Post-doctoral fellow at University of Virginia (2005-2009);

2010年-至今,先后任复旦大学生命科学学院副教授、研究员。

Associate Professor (2010) and Professor (2016-present) at the School of Life Sciences, Fudan University

 

主要研究方向 (Research Interests)

细胞膜离子通道结构与功能,以及离子通道异常引起的相关疾病的研究:

(1)细胞膜离子通道对醛固酮分泌及血压的调控;

(2)离子通道对神经细胞凋亡及神经损伤修复调控的研究。
Structure and function of ion channels, and human diseases associated with defects in ion channels.

 

获奖情况 (Awards)

1、2007年,American Heart Association,Posdoctoral Fellowship Award。
2、2009年,教育部自然科学二等奖(第3完成人)。
3、2013年,复星医药奖教金。

 

代表性成果

1. Yang, Tingting ,Zhang, Hai-Liang,Liang, Qingnan,Shi, Yingtang,Mei, Yan-Ai,Barrett, Paula Q,Hu C *. Small-Conductance Ca2+-Activated Potassium Channels Negatively Regulate Aldosterone Secretion in Human Adrenocortical Cells. Hypertension,2016,68(3):785~7953. 

2. Liu, Xiaoyu ,Yang, Tingting,Miao, Langxi,Mei, Yan-Ai,Hu C *. Leukotriene B4 Inhibits L-Type Calcium Channels via p38 Signaling Pathway in Vascular Smooth Muscle Cells. Cellular Physiology and Biochemistry,2015,37(5):1903~1913.

3. Yujie , Cui,Xiaoyu , Liu,Tingting, Yang,Yan-Ai, Mei,Hu C *. Exposure to extremely low-frequency electromagnetic fields inhibits T-type calcium channels via AA/LTE4 signaling pathway,Cell Calcium,2014,55(1):48~58.

4. Hu C, Rusin CG, Tan Z , Guagliardo NA and Barrett PQ. Zona glomerulosa cells of the mouse   adrenal cortex are intrinsic electrical oscillators. Journal of Clinical Investigation, 2012 ,122(6):2046-53.

5. Hu C, Seth D. DePuy, Junlan Yao, William McIntire, and Paula Q. Barrett. Protein kinase A activity controls the regulation of T-type Cav3.2 channels by Gbetagamma dimers.  J Biol Chem. 2009 :284, 7465-73

6. Hu C, Zheng Liu, Zhe-yu Gao, Zhi-Hong Zhang and Yan-Ai Mei. 2- Iodomelatonin   prevents apoptosis of cerebellar granule neurons via inhibition of A-type transient outward K+ currents. Journal of Pineal Research. 2005, 38(1):53-61.

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