胡长龙

基本信息

职称:研究员
电话:021-31246652
邮箱:clhu@fudan.edu.cn
地址:复旦大学生命科学学院 C209室

 

个人简介

男,博士,研究员,博士生导师。

2005年毕业于复旦大学生命科学学院,获理学博士学位;

Ph.D. from Fudan University (2005);

2005年7月至2009年12月,在美国弗吉尼亚大学从事博士后研究;

Post-doctoral fellow at University of Virginia (2005-2009);

2010年-至今,先后任复旦大学生命科学学院副教授、研究员。

Associate Professor (2010) and Professor (2016-present) at the School of Life Sciences, Fudan University

 

主要研究方向 (Research Interests)

细胞膜离子通道结构与功能,以及离子通道异常引起的相关疾病的研究:

(1)细胞膜离子通道对醛固酮分泌及血压的调控;

(2)离子通道对神经细胞凋亡及神经损伤修复调控的研究。
Structure and function of ion channels, and human diseases associated with defects in ion channels.

 

获奖情况 (Awards)

1、2007年,American Heart Association,Posdoctoral Fellowship Award。
2、2009年,教育部自然科学二等奖(第3完成人)。
3、2013年,复星医药奖教金。

 

代表性成果

1. Tian Y, Yang T, Yu S, Liu C, He M, Hu C *.Prostaglandin E2 increases migration and proliferation of human glioblastoma cells by activating transient receptor potential melastatin 7 channels. J Cell Mol Med. 2018;22(12):6327-6337.

2. Yang T, He M, Hu C *.Regulation of aldosterone production by ion channels: From basal secretion to primary aldosteronism. Biochim Biophys Acta Mol Basis Dis. 2018;1864(3):871-881.

3.  Yang, Tingting ,Zhang, Hai-Liang,Liang, Qingnan,Shi, Yingtang,Mei, Yan-Ai,Barrett, Paula Q,Hu C *. Small-Conductance Ca2+-Activated Potassium Channels Negatively Regulate Aldosterone Secretion in Human Adrenocortical Cells. Hypertension,2016,68(3):785~7953. 

4. Yujie , Cui,Xiaoyu , Liu,Tingting, Yang,Yan-Ai, Mei,Hu C *. Exposure to extremely low-frequency electromagnetic fields inhibits T-type calcium channels via AA/LTE4 signaling pathway. Cell Calcium,2014,55(1):48~58.

5. Hu C, Rusin CG, Tan Z , Guagliardo NA and Barrett PQ. Zona glomerulosa cells of the mouse   adrenal cortex are intrinsic electrical oscillators. Journal of Clinical Investigation, 2012 ,122(6):2046-53.

6. Hu C, Depuy SD, Yao J, McIntire WE, Barrett PQ. Protein kinase A activity controls the regulation of T-type CaV3.2 channels by Gbetagamma dimers. J Biol Chem. 2009 20;284(12):7465-73..

7.  Hu C, Zheng Liu, Zhe-yu Gao, Zhi-Hong Zhang and Yan-Ai Mei. 2- Iodomelatonin   prevents apoptosis of cerebellar granule neurons via inhibition of A-type transient outward K+ currents. Journal of Pineal Research. 2005, 38(1):53-61.

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