任国栋

基本信息

职称:研究员
电话:021-31246416
邮箱:gdren@fudan.edu.cn
地址:复旦大学生命科学学院 D403室

 

个人简介

男,研究员,博士生导师。2004年获复旦大学学士学位,2009年获复旦大学大学生物化学与分子生物学博士学位,2009至2013年在内布拉斯加州大学林肯分校从事博士后研究,2013年11月起受聘复旦大学生命科学学院青年研究员,2014年12月起晋升为研究员。

实验室主页:http://renlab.fudan.edu.cn/

 

主要研究方向 (Research Interests)

综合运用分子遗传学, 生物化学,细胞生物学及生物信息学等实验技术手段研究植物非编码RNA表观修饰、代谢与功能的分子基础。

 

获奖情况 (Awards)

2016年,国家优秀青年基金

 

代表性成果

1,Wang X#, Wang Y#, Dou Y#, Chen L, Wang J, Jiang N, Guo C, Yao Q, Wang C, Liu L, Yu B, Zheng B, Chekanova JA, Ma J, Ren G* (2018) Degradation of unmethylated miRNA/miRNA*s by a DEDDy-type 3’ to 5’ exoribonuclease ATRIMMER2 in Arabidopsis. Proc Natl Acad Sci USA,115 (28), E6659-E6667

2,Li Z, Wu S, Chen J, Wang X, Gao J, Ren G* and Kuai B* (2017), NYEs/SGRs-Mediated Chlorophyll Degradation is Critical for Detoxification during Seed Maturation in Arabidopsis. Plant J doi:10.1111/tpj.13710

3,  Wu S#, Li Z#, Yang L, Xie, Z, Chen J, Zhang W, Liu T, Gao S, Gao J, Zhu Y, Xin J, Ren G*, Kuai B* (2016) NON-YELLOWING2 (NYE2), a close paralog of NYE1, plays a positive role in chlorophyll degradation in Arabidopsis. Mol Plant. 9(4), 624-627

4,  Wang X#, Zhang S#, Dou Y#, Zhang C, Chen X, Yu B*, Ren G* (2015) Synergistic and independent actions of multiple terminal nucleotidyl transferases in 3’ tailing of small RNAs in Arabidopsis. PLoS Genet 11(4): e1005091.

5,  Ren G*, Chen X, Yu B* (2014) Small RNAs meet their targets: when methylation defends miRNAs from uridylation. RNA Biol. 11(9):1099-104(Invited Review)

6,  Ren G#, Xie M#, Zhang S, Vinovskis C, Chen X and Yu B* (2014) Methylation protects miRNAs from an AGO1-associated activity that uridylates 5' RNA fragments generated by AGO1 cleavage Proc Natl Acad Sci USA 111 (17), 6365-6370

7,  Ren G, Chen X, Yu B* (2012) Uridylation of miRNAs by HEN1 SUPPRESSOR1 in Arabidopsis. Curr Biol  22(8): 695-700

8,  Ren G, Xie M, Dou Y, Zhang S, Zhang C, Yu B* (2012) Regulation of small RNA abundance by TOUGH in Arabidopsis. Proc Natl Acad Sci USA 109(31): 12817-12821

9,  Xie M#, Ren G#, Zhang C, Yu B* (2012) The DNA and RNA binding protein FACTOR of DNA METHYLATION 1 requires XH domain-mediated complex formation for its function in RNA-directed DNA methylation. Plant J 72, 491–500

10,  Ren G, An K, Liao Y, Zhou X, Cao Y, Zhao H, Ge X, Kuai B* (2007) Identification of a Novel Chloroplast Protein Regulating Chlorophyll Degradation during Leaf Senescence in Arabidopsis. Plant Physiol 144: 1429-1441

 

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