沈文辉

基本信息

职称:教授
电话:021-516
30634
邮箱:whshen@fudan.edu.cn
地址:复旦大学生命科学学院 A401-6室

 

个人简介

男,1962年出生,博士,教授。1984年于北京农业大学获得学士学位,1986年于法国巴黎第六大学获得硕士学位,1989年于法国巴黎第十一大学获得植物细胞生理学博士学位。1989-1994在瑞士Friedrich Miescher研究所进行博士后研究,1994年获得法国国家科学研究中心植物分子生物学研究所(IBMP/CNRS)终身职位,1999年获得法国教育部植物生理学教授资格,2005年晋升为主任研究员并担任细胞生物学系主任。2008年依托复旦大学,获聘中国教育部长江讲座教授;2009年获得“千人计划”支持。现任BBA- Gene Regulatory Mechanisms和BMC Plant Biology副主编。在Nature Cell Biology, Current Biology., PNAS, Molecular and Cellular Biology, Molecular Biology of the Cell, Development, Plant Cell, Plant Journal, Plant Physiol.等发表学术论文60余篇。

 

 

主要研究方向 (Research Interests)

主要从事植物染色质组装和组蛋白修饰调控植物生长发育的分子机制研究。

 

获奖情况 (Awards)

 

 

代表性成果

1.  BERR, A, McALLUM, EJ, MENARD, R, MEYER, D, FUCHS, J, DONG, A, SHEN, W-H (2010).SET DOMAIN GROUP2 is required for H3K4 trimethylation associated with transcription activation and is crucial for both sporophyte and gametophyte development.  Plant Cell  (on line)

2.  XU, L, MENARD, R, BERR, A, FUCHS, J, COGNAT, V, MEYER, D, SHEN, W-H (2009).The E2 ubiquitin-conjugating enzymes, AtUBC1 and AtUBC2, play redundant roles and are involved in activation of FLC expression and repression of flowering in Arabidopsis thaliana.  Plant J.  57:279-288.

3.  XU, L, SHEN, W-H (2008).Polycomb silencing of KNOX genes confines shoot stem cell niches in Arabidopsis.  Curr. Biol.  18:1966-1971.

4.  XU, L, ZHAO, Z, DONG, A, SOUBIGOU-TACONNAT, L, RENOU, JP, STEINMETZ, A, SHEN, W-H (2008). Di- and tri- but not monomethylation on histone H3 lysine 36 marks active transcription of genes involved in flowering time regulation and other processes in Arabidopsis thaliana.  Mol. Cell Biol.  28, 1348-1360. (cover story)

5.  ZHU, Y, DONG, A, MEYER, D, PICHON, O, RENOU, JP, CAO, K, SHEN, W-H (2006) Arabidopsis NRP1 and NRP2 encode histone chaperones and are required for maintaining post-embryonic root growth.  Plant Cell, 18,2879-2892.

6.  ZHAO, Z, YU, Y, METER, D, WU, C, SHEN, W-H (2005) Prevention of early flowering by expression of FLOWERING LOCUS C requires methylation of histone H3 K36.  Nat Cell Biol. 7(12):1156-60.

7.  YU, Y, STEINMETZ, A, MEYER, D, SPENCER, B, SHEN, W-H (2003).The tobacco A-type cyclin, Nicta;CYCA3;2, at the nexus of cell division and differentiation.  Plant Cell, 15, 2763-2777.

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