王应祥

基本信息

职称:研究员  Professor
电话:021-51630537
邮箱:yx_wang@fudan.edu.cn
地址:复旦大学生命科学学院 E401-1室

 

个人简介

男,博士,研究员,博士生导师。2007年获华南农业大学植物营养学博士学位;2004-2005美国宾州州立大学生物系访问学者;2007-2011年分别在华南农业大学和复旦大学从事博士后研究;2013-2014美国宾州州立大学生物系访问学者;2011-至今 任复旦大学生命科学学院副研究员、研究员。

Ph.D studies in Plant Nutrition at South China Agricultural University (2007); Post-doctoral fellow at South China Agricultural University (2007-2009) and Fudan University (2009-2011); Associate Professor (2011-2015) and Professor (2016-present) at the School of Life Sciences, Fudan University.

 

主要研究方向 (Research Interests)

采用分子遗传学、细胞生物学、基因组学、蛋白质组学和生物信息学等手段, 以模式植物拟南芥、作物大豆、蔬菜番茄和黄瓜为材料,研究:(1)减数分裂过程中染色体相互作用的分子机理和表观遗传调控机制;(2)大豆适应逆境胁迫的关键基因克隆和功能分析。

Using molecular genetics, cell biology, genomics, proteomics and bioinformatics and other approaches in Arabidopsis, soybean, tomato and cucumber to study: (1) the molecular and epigenetic regulatory mechanisms in regulation of homologous chromosome interactions during meiosis; (2) the identification of genes required from soybean in adaption to abiotic stresses.

 

获奖情况 (Awards)

教育部青年长江学者,2016

上海市青年启明星计划,2013

复旦大学“卓学计划”,2012

复星医药奖教金(一等奖)2012,(特等奖)2016

 

代表性成果[Selected Publications; total 25; * corresponding author(s)]

1. Su H#, Chen ZH#, Huang JY, Lin J, Copenhaver GP, Ma H, Wang YX*. Arabidopsis RAD51, RAD51C and XRCC3 proteins form a complex and facilitate RAD51 localization on chromosomes for meiotic recombination. PLOS Genetics, 2017, e1006827. doi: 10.1371

2. Zhou L, Han JL, Chen YL, Wang YX*, Liu YG*. Bivalent Formation 1, a plant-conserved gene, encodes an OmpH/coiled-coil motif-containing protein required for meiotic recombination in rice. Journal of Experimental Botany, 2017, 68:2163-2174. doi:10.1093.

3. Wang J, Niu BX, Huang JY, Wang HK, Yang XH, Dong AW, Mackaroff C, Ma H, Wang YX*. Arabidopsis MMD1 Ensures the Progression of Male Meiotic Chromosome Condensation and Directly Regulates the Expression of Condensin Gene CAP-D3. Plant Cell. 2016, 28:1894-1909.

4. Niu BX, Wang LD, Zhang LS, Ren D, Ren R, Copenhaver GP, Ma H*, Wang YX*. The Arabidopsis CDC20.1 Gene is Required for Normal Meiotic Spindle Assembly and Chromosome Segregation. Plant Cell. 2015, 27:1-16.

5. Huang JY, Cheng ZH, Wang C, Hong Y, Su H, Wang H, Copenhaver GP, Ma H*, Wang YX*. Formation of interference-sensitive meiotic crossovers requires sufficient DNA leading strand elongation. PNAS, 2015, 112:12534-9.

6. Wang YX, Xiao R, Wang HF, Cheng ZH, Li WX, Zhu GF, Wang Y, Ma H. The Arabidopsis RAD51 paralogs RAD51B, RAD51D and XRCC2 play partially redundant roles in somatic DNA repair and gene regulation. New Phytologist, 2014, 201: 292-304.

7. Wang YX, Cheng ZH, Huang JY, Shi Q, Hong Y, Copenhaver GP, Gong ZZ, Ma H*. The DNA Replication Factor RFC1 is Required for Interference-Sensitive Meiotic Crossovers in Arabidopsis. PLOS Genetics, 2012, 10.1371:1003039.

8. Wang YX and Ma H*. Development: A pathway to plant female germ cells. Current Biology, 2011, 21: R476-478.

9. Chang F, Wang YX, Wang SS, Ma H. Molecular control of microsporogenesis in Arabidopsis. Current Opinion in Plant Biology, 2011, 14: 66-73 (#Co-first author).

10. Yang HX, LU PL, Wang YX*, Ma H*. Uncover the transcriptome landscape in Arabidopsis meio­cytes using high-throughput sequencing: the conservation and divergence of the meiotic process. Plant J, 2011, 65: 503-516.

 

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