印春华

基本信息

职称:教授
电话:021-516
30558
邮箱:chyin@fudan.edu.cn
地址:复旦大学生命科学学院 A511室

 

个人简介

男,1965年出生,博士,教授。1982-1986年就读中国药科大学药学系,获理学学士学位,1988-1993年在中国药科大学攻读研究生,获理学(药剂学)博士学位。1994-1996年在军事医学科学院从事博士后研究,1996-1999年任复旦大学生命科学学院副教授,2000年起任复旦大学生命科学学院遗传工程国家重点实验室教授,进行生物大分子药物与新型给药系统、药用载体材料与分子药剂学、新药与药物新剂型等研究工作。

 

主要研究方向 (Research Interests)

用分子药剂学、药代动力学、药物分析学、药用材料学等手段,研究改善蛋白质与多肽、核酸、抗肿瘤药物及难溶性药物等功效的新型载体的加工、改性、组装、体内外作用机理及其给药系统的设计。

 

获奖情况 (Awards)

曾获教育部科学技术奖一等奖(第一完成人),上海市科学技术奖二等奖(第一完成人)等。

 

代表性成果

1.   Chunbai He, Yiping Hu, Lichen Yin, Cui Tang, Chunhua Yin* (2010). Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles. Biomaterials, 31(13):3657-3666.
2.   Lichen Yin, Jieying Ding, Jing Zhang, Chunbai He, Cui Tang, Chunhua Yin* (2010). Polymer integrity related absorption mechanism of superporous hydrogel containing interpenetrating polymer networks for oral delivery of insulin. Biomaterials, 31(12):3347-3356.
3.   Lichen Yin, Jieying Ding, Chunbai He, Liming Cui, Cui Tang*, Chunhua Yin* (2009). Drug permeability and mucoadhesion properties of thiolated trimethyl chitosan nanoparticles in oral insulin delivery. Biomaterials, 30(29):5691-5700.
4.   Lichen Yin, Likun Fei, Fuying Cui, Cui Tang*, Chunhua Yin* (2007). Superporous hydrogels containing poly(acrylic acid-co-acrylamide)/ O-carboxymethyl chitosan interpenetrating polymer networks. Biomaterials, 28:1258-1266.
5.   Xin Zhao, Lichen Yin, Jieying Ding, Cui Tang, Shaohua Gu, Chunhua Yin*, Yumin Mao(2010). Thiolated trimethyl chitosan nanocomplexes as gene carriers with high in vitro and in vivo transfection efficiency. J. Control Release, 144:46-54
6.   Ziming Zhao, Miao He, Lichen Yin, Jiamin Bao, Lili Shi, Bingqing Wang, Cui Tang, Chunhua Yin* (2009). Biodegradable nanoparticles based on linoleic acid and poly(β-malic acid) double grafted chitosan derivatives as carriers of anticancer drugs. Biomacromolecules, 10:565-572.  

 

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