
基本信息
职称:研究员
电话:021-31246742
邮箱:chend@fudan.edu.cn
地址:复旦大学生命科学学院E301-2
个人简介
2008年毕业于中国科学技术大学,细胞生物学博士。毕业后赴美国贝勒医学院从事生物质谱和蛋白质组学博士后研究工作。2012年全职回国在北京蛋白质组研究中心任副研究员、研究员。2013年入选北京市第九批“海聚工程”,2014年入选“北京市优秀青年人才”。2015年起受聘为复旦大学生命科学学院研究员。
主要研究方向 (Research Interests)
获奖情况 (Awards)
2013年北京市第九批“海聚工程”
2014年北京市第七批“优秀青年人才”
代表性成果
1. Feng J#, Ding C#, *, Qiu N#, Ni X#, Zhan D#, Liu W, Xia X, Li P, Lu B, Zhao Q, Nie P, Song L, Zhou Q, Lai M, Guo G, Zhu W, Ren J, Shi T*, Qin J*. Firmiana: Towards a One-stop Proteomic Cloud Platform for Data Processiong and Analysis. DOI: 10.1038/nbt.3825, Nature Biotechnology, 2017. (#Co-first author, *Co-corresponding author)
2. Zhou Q, Liu M, Xia X, Gong T, Feng J, Liu W, Liu Y, Zhen B, Wang Y, Ding C*, Qin J*. A Mouse Tissue Transcription Factor Atlas. DOI: 10.1038/ncomms15089, Nature Communications, 2017. (*Co-corresponding author)
3. Lang X, Tang T, Jin T, Ding C*, Zhou R*, Jiang W*. TRIM65 Catalyzed Ubiquitination is Essential for MDA5-mediated Antiviral Innate Immunity. Journal of Experimental Medicine. 2017.2.1, 214(2): 459~473. (*Co-corresponding author)
4. Shi W, Li K, Song L, Liu M, Wang Y, Liu W, Xia X, Qin Z, Zhen B, Wang Y, He F, Qin J, Ding C. TFRE on Tip (TOT): A sensitive approach for large-scale endogenous transcription factor quantitative identification. Analytical Chemistry. 2016.12.20, 88(24): 11990~11994.
5. Liu M, Ge R, Liu W, Liu Q, Xia X, Lai M, Liang L, Li C, Song L, Zhen B, Qin J, Ding C. Differential proteomics profiling identifies lipid droplet proteins and biological functions in high fat diet induced fatty livers. J Lipid Res. 2017 Feb 8. pii: jlr.M071407. doi: 10.1194/jlr.M071407. [Epub ahead of print]
6. Wei J, Zhang Y, Jia Q, Liu M, Li D, Zhang Y, Song L, Hu Y, Xian M, Yang H, Ding C*, Huang L*. Systematic investigation of transcription factors critical in the protection against cerebral ischemia by Danhong injection. Sci Rep. 2016 Jul 19;6:29823. (*Co-corresponding author)
7. Ding C, Chan D, Liu W, Liu M, Li D, Li C, Jin J, Malovannaya A, Jung SY, Zhen B, Wang Y, Qin J. Proteome-wide profiling of activated transcription factors with a concatenated tandem array of transcription factor response elements. Proc Natl Acad Sci U S A. 2013 Apr 23;110(17):6771-6.
8. Ding C, Li Y, Guo F, Jiang Y, Ying W, Li D, Yang D, Xia X, Liu W, Zhao Y, He Y, Li X, Sun W, Liu Q, Song L, Zhen B, Zhang P, Qian X, Qin J, He F. A cell-type-resolved liver proteome. Mol Cell Proteomics. 2016 Oct;15(10):3190-3202.
9. Ding C, Jiang J, Wei J, Liu W, Zhang W, Liu M, Fu T, Lu T, Song L, Ying W, Chang C, Zhang Y, Ma J, Wei L, Malovannaya A, Jia L, Zhen B, He F, Qian X, Qin J. A Fast Workflow for Identification and Quantification of Proteomes. Molecular & Cellular Proteomics. 2013 Aug;12(8):2370-80.
10. Foulds CE#, Feng Q#, Ding C#, Bailey S, Hunsaker TL, Malovannava A, Hamilton RA, Gates LA, Zhang Z, Li C, Chan D, Bajaj A, Callaway CG, Dean P. Edwards DP, Lonard DM, Tsai SY, Tsai MJ, Qin J, and Bert W. O'Malley BW. Proteomic Analysis of Coregulators Bound to ER on DNA and Nucleosomes Reveals Dynamic ‘Poised’ Complexes. Molecular Cell. 2013 Jul 25;51(2):185-99. (#Co-first author)
11. Ding C, Li Y, Kim BJ, Malovannaya A, Jung SY, Wang Y, Qin J. Quantitative analysis of cohesin complex stoichiometry and SMC3 modification-dependent protein interactions. J Proteome Res. 2011 Aug 5;10(8):3652-9.
12. Ding C, Wei H, Sun R, Zhang J, Tian Z. Hepatocytes Proteomic Alteration and seroproteome analysis of HBV Transgenic Mice. Proteomics. 2009 Jan;9(1):87-105.
13. Wei J#, Ding C#, Zhang J, Mi W, Zhao Y, Liu M, Fu T, Zhang Y, Ying W, Cai Y, Qin J, Qian X. High-throughput absolute quantification of proteins using an improved two-dimensional reversed-phase separation and quantification concatemer (QconCAT) approach. Anal Bioanal Chem. 2014 406:4183–4193 (#Co-first author)