徐颖

基本信息

职称:副教授
电话:021-516
30587
邮箱:yingxu2520@fudan.edu.cn
地址:复旦大学生命科学学院C501

 

个人简介

    女,1979年出生,博士,副教授。1998-2002年就读于烟台大学生物化学理工学院,获得生物化学学士学位, 2002-2007年就读于复旦大学生命科学学院,获得微生物学博士学位。2007-2009年在复旦大学医学院从事博士后研究。2009年-至今在复旦大学生命科学学院任讲师、副教授。

B. A. degree in Biochemistry in 2002 from Yantai University and Ph. D. in Microbiology from Fudan University in 2007. Post-doctoral fellow at School of Basic Medical of Fudan University from 2007 to 2009; Lecturer and Associate professor of the School of Life Sciences, Fudan University, since 2009.

 

主要研究方向 (Research Interests)

1. 新型抗结核疫苗及其免疫机制的研究。

2. 结核杆菌和相关蛋白与宿主相互作用的研究。

1. Study of the novel vaccine against Mycobacterium tuberculosis and its immune mechanism.

2. Study of the interaction between Mycobacterium tuberculosis and the host.

 

 获奖情况 (Awards)

 

 

 代表性成果

1. Li G, Liu G, Song N, Kong C, Huang Q, Su H, Bi A, Luo L, Zhu L, Xu Y*, Wang H. 2015. A novel recombinant BCG-expressing pro-apoptotic protein BAX enhances Th1 protective immune responses in mice. Mol Immunol.;66(2):346-356.

2. Xu Y, Yang E, Huang Q, Ni W, Kong C, Liu G, Li G, Su H, Wang H. 2015.PPE57 induces activation of macrophages and drives Th1-type immune responses through TLR2. J Mol Med (Berl). 2015 Jan 15.

3. Xu Y, Yang E, Wang J, Li R, Li G, Liu G, Song N, Huang Q, Kong C, Wang H.2014. Prime-boost bacillus Calmette-Guérin vaccination with lentivirus-vectored and DNA-based vaccines expressing antigens Ag85B and Rv3425 improves protective efficacy against Mycobacterium tuberculosis in mice. Immunology. 143(2):277-86.

4. Xu Y, Liu W, Shen H, Yan J, Yang E, Wang H.2010.Recombinant Mycobacterium bovis BCG expressing chimaeric protein of Ag85B and ESAT-6 enhances immunostimulatory activity of human macrophages. Microbes Infect. 12(8-9):683-9.

5. Xu Y, Liu W, Shen H, Yan J, Qu D, Wang H.2009.Recombinant Mycobacterium bovis BCG expressing the chimeric protein of antigen 85B and ESAT-6 enhances the Th1 cell-mediated response. Clin Vaccine Immunol. 16(8):1121-6.

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