The Ministry of Education (MOE) Key Laboratory of Contemporary Anthropology (KLCA) at Fudan University was developed from the Lab of Human Population Genetics and Complex Diseases (est. 1997) in December of 2005 and was approved by the MOE of China in 2008. Based on the Biology discipline and the sub- disciplines of Genetics and Human Biology, MOE-KLCA focuses on the researches of Molecular Anthropology and has been evaluated as the Outstanding MOE Key Laboratory in 2010. In 2012, MOE-KLCA was approved as the ‘National Base of International Science and Technology Cooperation’ and ‘Intelligence Recruitment Base of Human Genetics’ of the 2011 Plan.

 

       MOE-KLCA is devoted to researches on human population genetics and its applications, aims at the physical, physiological, and pathological variations between individuals/populations and their evolutional history, and provides methods and tools for disease prevention and humanity researches. The inter-disciplinary fields of MOE-KLCA also encompasses genetic structure of human populations, evolution and adaption of the human genome, physical anthropology, ancient DNA of humankind, molecular epidemiology, computational biology, linguistic anthropology, ethnology, archaeological anthropology, etc.

 

       MOE-KLCA has been supported financially by Chinese governments via Ministry of Science and Technology of China, National Natural Science Foundation of China, Ministry of Health of China, etc. Fundings include National Science and Technology Major Project, 973 Project, 863 Project, National Natural Science Foundation of China Major Project, National Science and Technology Support Key Program, etc. Besides, MOE-KLCA is also the member of eight international collaboration projects, including the Genographic Project, the PanAsia SNP project, the HapMap project, the RECO project, and etc. The sample repository of MOE-KLCA includes 200 thousand DNA samples from modern humans and 3 thousand ancient DNAs, which cover human populations in the majority of East Asia and throughout China. MOE-KLCA plays leading roles in human population genetics, medical genetics, molecular epidemiology, and computational biology. Our main findings include: genetic structures of East Asians, origins and genomics of admixed populations, genetic dissection of human physiological phenotypes, pharmagenomics and evolution. MOE-KLCA is one of the ten laboratories of the Genographic Project, covering East Asia and Southeast Asia.

 

       The faculties of MOE-KLCA include 16 Professors/Investigators, 11 Associate Professors/Associated Investigators, 1 Senior Engineer, 5 Lecturers/Assistant Investigators. Our innovative team is mainly composed of young scholars, some of which have also been supported by the 1000 Plan, the NSFC grant for National Outstanding Young Scholars, the Organization Department of the CPC Central Committee, New Century Excellent Talents in University Program of MOE, etc. This team also joins together the researchers of three ascendent disciplines of anthropology, genetics, and historical geography in Fudan University. Our researches integrate life sciences with mathematics, medicine, and humanity.  We also integrate the basic researches and applied researches.

The experimental base of international first class has created many important scientific findings with global impacts. MOE-KLCA is now a key center of biological anthropology in the world and leader of the field in China. Our lab has established a qualified education program for Human Biology. MOE-KLCA is the first MOE-authorized institute to grant the PhD degree of Human Biology. In addition to Human Biology, MOE-KLCA also recruits master and Ph.D. students in Genetics and Bioinformatics.

 

       The scientific achievements of MOE-KLCA have been world-widely recognized. We published dozens of research papers in high-impact scientific journals, including Science, Nature, JAMA, JCI, AJHG, and PNAS. We also received National Prize of Natural Science and ten other national, ministerial, and provincial awards for science and technology development. These achievements also attribute to our researchers and students, including four winners of the Challenge Cup, three winners and two nominees of Author of National Excellent Doctoral Dissertation of China. The visiting scholars to MOE-KLCA have added up to more than 30.

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