姓名：刘瑞
职称：青年副研究员
职务：青年副研究员
电子邮箱：liur@fudan.edu.cn
办公地点：A201-5
办公电话：021-31246545
个人网页/课题组主页：
研究方向
以结构信息为基础的神经生物学研究
个人简介
2008年获复旦大学生物技术专业学士学位；2016年获复旦大学生物物理学专业博士学位；2014年至2019年，在中国科学院上海生命科学研究院杜嘉木课题组从事博士后研究；2019年至2021年，在南方科技大学历任高级研究学者和研究助理教授；2021年3月加入复旦大学生命科学学院鲁伯埙课题组任青年副研究员。
招生专业
生物物理学
代表性论文和论著
Zhou Z#, Pan Q#, Lv X#, Yuan J#, Zhang M, Ke M, Mo X,Xie Y,Chen T, Liu Y, Yin F, Liu L, Zhou Y, You C, Qiao K, Liu R*, Li Z*, Wong N*. Structural insights into the inhibition of bacterial RecA by naphthalene polysulfonated compounds. iScience 2021, 24(1): 101952. IF4.447
Tan LM#, Liu R#, Gu BW, Zhang CJ, Luo J, Guo J, Wang Y, Chen L, Du X, Li S, Shao CR, Su YN, Cai XW, Lin RN, Li L, Chen S, Du J*, He XJ*. Dual Recognition of H3K4me3 and DNA by the ISWI Component ARID5 Regulates the Floral Transition in Arabidopsis. Plant Cell 2020, 32(7): 2178-2195. IF9.618
Liu R#, Li X#, Chen W, Du J*. Structure and mechanism of plant histone mark readers. Sci China Life Sci 2018, 61(2): 170-177. IF4.611(review article)
Liu R, Hu XJ*, Ding Y*. Rational design of a pH-insensitive cyan fluorescent protein CyPet2 based on the CyPet crystal structure. FEBS Lett 2017, 591(12): 1761-1769. IF3.057
Liu R#, Yang G#, Zhou MH#, He Y, Mei YA*, Ding Y*. Flotillin-1 downregulates K(+) current by directly coupling with Kv2.1 subunit. Protein Cell 2016, 7(6): 455-460. IF10.164
Liu R#, Liang QN#, Du SQ, Hu XJ*, Ding Y*. The crystal structure of red fluorescent protein TagRFP-T reveals the mechanism of its superior photostability. Biochem Biophys Res Commun 2016, 477(2): 229-234. IF2.985
Liang Q#, Liu R#, Du S, Ding Y*. Structural insights on the catalytic site protection of human carbonyl reductase 1 by glutathione.J Struct Biol 2015, 192(1): 138-144. IF3.071
Li X#, Harris CJ#, Zhong Z, Chen W, Liu R, Jia B, Wang Z, Li S, Jacobsen SE*, Du J*. Mechanistic insights into plant SUVH family H3K9 methyltransferases and their binding to context biased non-CG DNA methylation. Proc Natl Acad Sci USA. 2018; 115: E8793-E8802. IF9.412
Yang Z#, Qian S#, Scheid RN, Lu L, Chen X, Liu R, Du X, Lv X, Boersma MD, Scalf M, Smith LM, Denu JM, Du J*, Zhong X*. EBS is a bivalent histone reader that regulates floral phase transition in Arabidopsis. Nat Genet. 2018; 50: 1247-1253.IF27.603
Qian S#, Lv X#, Scheid RN#, Lu L, Yang Z, Chen W, Liu R, Boersma MD, Denu JM, Zhong X*, Du J*. Dual recognition of H3K4me3 and H3K27me3 by a plant histone reader SHL. Nat Commun. 2018; 9: 2425.IF12.121
Li S, Yang Z, Du X, Liu R, Wilkinson AW, Gozani O, Jacobsen SE, Patel DJ, Du J*. Structural Basis for the Unique Multivalent Readout of Unmodified H3 Tail by Arabidopsis ORC1b BAH-PHD Cassette. Structure. 2016; 24: 486-494 IF4.862
Yuan W, Luo X, Li Z, Yang W, Wang Y, Liu R, Du J and He Y *. A cis cold memory element and a trans epigenome reader mediate Polycomb silencing of FLC by vernalization in Arabidopsis. Nat Genet. 2016, 48: 1527-1534. IF27.603