姚红艳

发布时间：2021-06-27浏览次数：4652

基本信息

姓名：姚红艳

职称：副研究员

电子邮箱：hyao@fudan.edu.cn

办公地点：复旦生科院D109室

办公电话：021-31246724

研究方向

发展高通量植物脂质组学技术，结合生物统计、生物化学、细胞生物学、分子遗传学等学科方法，研究植物环境适应的脂质代谢基础及分子调控机制；脂质介导的细胞器动态平衡机制。

个人简介

姚红艳，女，于1999年、2003年分别获山东大学学士、硕士学位，2009年获上海交通大学生物医学工程（生物技术）专业博士学位。2007-2008年，美国密苏里大学、Danforth植物科学中心，访问学者。2009-2019年，中科院上海植物生理生态研究所（现中科院分子植物卓越创新中心），助理研究员、副研究员。2019年-至今，复旦大学生命科学学院，副研究员。在Nature Communications、PNAS及Plant Cell等上发表SCI论文20余篇。部分工作被Nature Plants作为“研究亮点”专文评述，Faculty of 1000 所推荐，以及被重要专著《Arabidopsis Book》中“Root Hairs”章节所引用。撰写相关的综述论文，发表在重要期刊《Current opinion in Plant Biology》、《Journal of Integrative Plant Biology》、《Journal of Biological Methods》上，并多次被相关领域文章所引用。现任上海植物生物技术学术委员会委员，中国生物物理学会代谢组学分会秘书。

科研项目

1. 国家自然科学基金委员会, 面上项目, 31870280, 磷脂酰肌醇转运蛋白（PITP）调控拟南芥叶绿体发育的作用及机制, 2019-01-01至 2022-12-31,结题，主持

2. 国家自然科学基金委员会, 重大研究计划, 91954206,磷脂分子参与植物细胞器互作及自噬的调控机制, 2020-01-01至 2023-12-31,结题，骨干

3. 国家重点研发计划，2016YFD0100902-09，水稻品质性状的分子调控网络分析，2016-7-1至2020-12-31，65万，结题，骨干

4.国家自然科学基金委员会, 青年项目, 31400261, β-酮酰-ACP合酶I及脂肪酸调控植物根毛发生的分子机制研究, 2015-01-01 至 2017-12-31, 结题，主持

5. 国家自然科学基金国际(地区)合作与交流项目（NSFC-NWO 项目），31110236，环境信号调控植物根系发育的机理研究，2012-01-01至2015-12-31，结题，参与

6. 中国科学院上海生命科学研究院优秀青年人才领域前沿项目，No.2011KIP304，磷脂酸调控植物细胞囊泡运输和生长素运输机制的研究，2011-06-01至2013-06-30，结题，主持

授课情况

主要承担专业必修课《生物化学》的教学工作，参与“思政讨论课”、“生命科学交叉前沿专题”课程的教学工作。

招生专业

生物化学与分子生物学、生物与医药

代表性论文

1. Lyu MA^#, Du H^#, Yao H^#, Zhang Z^#, Chen G, Huang Y, Ni X, Chen F, Zhao YY, Tang Q, Miao F, Wang Y, Zhao Y, Lu H, Fang L, Gao Q, Qi Y, Zhang Q, Zhang J, Yang T, Cui X, Liang C, Lu T and Zhu XG. A dominant role of transcriptional regulation during the evolution of C4 photosynthesis in Flaveria species. Nat Commun*. 2025, 16:1643.

2. Qian W, Tang H and Yao H. Lipidomics and temporal-spatial distribution of organelle lipid. J. Biol. Methods.* 2025, 12: e99010049.

3. Yao H^#, Lu Y^#, Yang X^#, Wang X, Luo Z, Lin D, Wu J* and Xue H. Arabidopsis Sec14 proteins (SFH5 and SFH7) mediate inter-organelle transport of phosphatidic acid and regulate chloroplast development. Proc. Natl. Acad. Sci. U S A2023, 120: e2221637120. (research highlights in Nature Plants*)

4. Qian W, Zhu Y, Chen Q, Wang S, Chen L, Liu T, Tang H* and YaoH. Comprehensive metabolomic and lipidomic alterations in response to heat stress during seed germination and seedling growth of Arabidopsis. Front. Plant Sci.*2023, 14.

5. Du X, Yao H, Luo P, Tang X, Xue H. Cytidinediphosphate diacylglycerol synthase-Mediated phosphatidic acid metabolism is crucial for early embryonic development of Arabidopsis. PLoS Genet.* 2022, 18: e1010320.

6. Lin D^#, Yao H^#, Jia L, Tan J, Xu Z, Zheng W* and Xue H. Phospholipase D-derived phosphatidic acid promotes root hair development under phosphorus deficiency by suppressing vacuolar degradation of PIN2. New Phytol.* 2020, 226: 142–155.

7. Chen C, He B, Liu X, Ma X, Liu Y, Yao H, Zhang P, Yin J, Wei X, Koh HJ, Yang C, Xue HW, Fang Z, Qiao Y. Pyrophosphate-fructose 6-phosphate 1-phosphotransferase (PFP1) regulates starch biosynthesis and seed development via heterotetramer formation in rice (Oryza sativa L.). Plant Biotechnol J. 2020, 18: 83-95.

8. Yao H and Xue H. Phosphatidic acid (PA) plays key roles regulating plant development and stress responses. J. Integr. Plant Biol.* 2018, 60: 851-863.

9. Wang Y, Yao H* and Xue H. Lipidomic profiling analysis reveals the dynamics of phospholipid molecules in Arabidopsis thaliana seedling growth. J. Integr. Plant Biol. 2016, 58:890-902. (Cover*).

10. Deng T^#, Yao Y^#, Wang J^#, Wang J, Xue H* and Zuo K*. GhLTPG1, a cotton GPI-anchored lipid transfer protein, regulates the transport of phosphatidylinositol monophosphates and cotton fiber elongation. Sci. Rep.2016, 6:26829.

11. Gao Q^#, Lu Y^#, Yao H^#, Xu Y, Huang W and Wang C. Phospholipid homeostasis maintains cell polarity, development and virulence in metarhizium robertsii. Environ. Microbiol.* 2016, 18:3976-3990.

12. Yu F^#, He F^#, Yao H, Wang C, Wang J, Li J, Qi X, Xue H, Ding J and Zhang P. Structural basis of intramitochondrial phosphatidic acid transport mediated by Ups1-Mdm35 complex. EMBO Rep.2015, 16:813-823. (recommended by F1000 Prime*).

13. Yao H, Wang G and Wang X. Nuclear translocation of proteins and the effect of phosphatidic acid. Plant Signal. & Behav*. 2014, 9:12, e977711.

14. Yao H^#, Wang G^#, Guo G and Wang X. Phosphatidic acid interacts with a MYB transcription factor and regulates its nuclear localization and function in Arabidopsis. Plant Cell2013, 25: 5030-5042. (recommended by F1000 Prime*).

15. Yao H and Xue H. Signals and mechanisms affecting vesicular trafficking during root growth. Curr. Opin. Plant Biol.*2011,14: 571-579.

16. Yao H^#, Zhang T^#, Xue H, Tang K* and Li R. Biomimetic affinity purification of Candida antarctica* lipase B. J. Chromatogr. B2011, 879: 3896-3900.

姚红艳

2. Qian W, Tang H and Yao H*. Lipidomics and temporal-spatial distribution of organelle lipid. J. Biol. Methods. 2025, 12: e99010049.

3. Yao H#, Lu Y#, Yang X#, Wang X, Luo Z, Lin D, Wu J* and Xue H*. Arabidopsis Sec14 proteins (SFH5 and SFH7) mediate inter-organelle transport of phosphatidic acid and regulate chloroplast development. Proc. Natl. Acad. Sci. U S A2023, 120: e2221637120. (research highlights in Nature Plants)

4. Qian W, Zhu Y, Chen Q, Wang S, Chen L, Liu T, Tang H* and YaoH*. Comprehensive metabolomic and lipidomic alterations in response to heat stress during seed germination and seedling growth of Arabidopsis. Front. Plant Sci.2023, 14.

5. Du X, Yao H, Luo P, Tang X, Xue H*. Cytidinediphosphate diacylglycerol synthase-Mediated phosphatidic acid metabolism is crucial for early embryonic development of Arabidopsis. PLoS Genet. 2022, 18: e1010320.

6. Lin D#, Yao H#, Jia L, Tan J, Xu Z, Zheng W* and Xue H*. Phospholipase D-derived phosphatidic acid promotes root hair development under phosphorus deficiency by suppressing vacuolar degradation of PIN2. New Phytol. 2020, 226: 142–155.

8. Yao H and Xue H*. Phosphatidic acid (PA) plays key roles regulating plant development and stress responses. J. Integr. Plant Biol. 2018, 60: 851-863.

9. Wang Y, Yao H* and Xue H*. Lipidomic profiling analysis reveals the dynamics of phospholipid molecules in Arabidopsis thaliana seedling growth. J. Integr. Plant Biol. 2016, 58:890-902. (Cover).

10. Deng T#, Yao Y#, Wang J#, Wang J, Xue H* and Zuo K*. GhLTPG1, a cotton GPI-anchored lipid transfer protein, regulates the transport of phosphatidylinositol monophosphates and cotton fiber elongation. Sci. Rep.2016, 6:26829.

11. Gao Q#, Lu Y#, Yao H#, Xu Y, Huang W and Wang C*. Phospholipid homeostasis maintains cell polarity, development and virulence in metarhizium robertsii. Environ. Microbiol. 2016, 18:3976-3990.

12. Yu F#, He F#, Yao H, Wang C, Wang J, Li J, Qi X, Xue H*, Ding J* and Zhang P*. Structural basis of intramitochondrial phosphatidic acid transport mediated by Ups1-Mdm35 complex. EMBO Rep.2015, 16:813-823. (recommended by F1000 Prime).

13. Yao H*, Wang G and Wang X. Nuclear translocation of proteins and the effect of phosphatidic acid. Plant Signal. & Behav. 2014, 9:12, e977711.

14. Yao H#, Wang G#, Guo G and Wang X*. Phosphatidic acid interacts with a MYB transcription factor and regulates its nuclear localization and function in Arabidopsis. Plant Cell2013, 25: 5030-5042. (recommended by F1000 Prime).

15. Yao H and Xue H*. Signals and mechanisms affecting vesicular trafficking during root growth. Curr. Opin. Plant Biol.2011,14: 571-579.

16. Yao H#, Zhang T#, Xue H, Tang K* and Li R*. Biomimetic affinity purification of Candida antarctica lipase B. J. Chromatogr. B2011, 879: 3896-3900.