葛晓春

发布者:王诗铭发布时间:2021-06-27浏览次数:404

教师基本信息

姓名:葛晓春

职称:教授

职务:教师

电子邮箱:xcge@fudan.edu.cn

办公地点:生科院楼D417

办公电话:021-31246642

个人网页/课题组主页:


研究方向

植物分子生物学、逆境生物学


个人简介

复旦大学本科、硕士及博士学位,2003-2005美国Donald Danforth Plant Science Center 博士后2003年起先后任复旦大学生物化学系副教授及教授职位。已获得7项 国家自然科学基金项目、2项上海市科委重点项目和1项上海市人才计划项目的资助;作为项目核心成员参与两项国家重大转基因专项“重要性状基因克隆及功能验证”以及“水稻节水稳产新基因及启动子的克隆与功能验证”以及1项国家973项目“作物水分高效利用机理与调控的基础研究”;2006年入选上海市浦江人才计划。在 Current Biology, Molecular Plant, Plant Cell, Plant Journal, Plant Physiology, EMBO ReportsPlant Molecular Biology等杂志上发表通讯或者第一作者论文多篇,申请专利10项,有7项已获得授权;做为主编出版译著《蛋白质结构与功能》,并参与植物分子生物学专业重要教材《植物生理学》的翻译及编辑工作。


研究兴趣

全世界范围内,由于环境胁迫因素引起的作物产量损失不计其数。实验室主要致力于揭示植物应对环境因素变化的机制,以及利用已拥有专利的基因来提高作物抗非生物逆境及抗除草剂的能力。实验室的主要研究方向为:1)植物抗逆境相关基因的功能研究,包括抗旱、抗除草剂等基因的功能研究;2)细胞死亡调控相关基因在植物逆境响应信号途径中的功能。


授课情况

主讲本科生课程《核酸的化学与生物学》;研究生课程《核酸化学》


招生专业

植物分子生物学,生物化学,生物工程


代表性论文和论著

1. Gu Z, Pan W, Chen W, Ge X*. (2019) New perspectives on the plant PARP family: Arabidopsis PARP3 is inactive, and PARP1 exhibits predominant poly (ADP-ribose) polymerase activity in response to DNA damage. BMC plant Biol., 19: 364

2. Yao L, Cheng X, Gu Z, Huang W, Li S, Wang L, Wang Y, Xu P, Ma H, Ge X*. (2018) AWPM-19 family protein OsPM1 mediates abscisic acid influx and drought response in rice. Plant Cell, 30: 1258-1276

3. Jin Y, Pan W, Zheng X, Cheng X, Liu M, Ma H*, Ge X*. (2018) OsERF101, an ERF family transcription factor, regulates drought stress response in reproductive tissues. Plant Mol. Biol., 98:51-65

4. Liu C, Wu Q, Liu W, Gu Z, Wang W, Xu P, Ma H, Ge X*. (2017) Poly(ADP-ribose) polymerases regulate root cell division and inhibition of PARP activities enhances root development. J. Integr. Plant Biol., 59(7): 459-474   

5. Guo C, Yao L, You C, Wang S, Cui J, Ge X*, Ma H*. (2016) MID1 plays an important role in response to drought stress during reproductive development. Plant J., 88(2): 280-293.

6. Zhang H, Gu Z, Wu Q, Yang L, Liu C, Ma H, Xia Y, Ge X*. (2015) Arabidopsis PARG1 is the key factor promoting cell survival among the enzymes regulating post-translational poly(ADP-ribosyl)ation. Sci. Rep., 5:15892. doi: 10.1038/srep15892.   .

7. Jin Y, Yang H, Wei Z, Ma H, Ge X*. (2013) Rice male development under drought stress: phenotypic changes and stage-dependent transcriptomic reprogramming. Mol. Plant, 6: 1630-45.     

9. Wang H, Lu Y, Liu P, Wen W, Zhang J, Ge X*, Xia Y*. (2013) The ammonium/ nitrate ratio is an input signal in the temperature-modulated, SNC1-mediated and EDS1-dependent autoimmunity of nudt6-2nudt7. Plant J., 73: 262-275.

10. Wang H, Wang S, Lu Y, Alvarez S, Hicks L, Ge X*, Xia Y*. (2012) Proteomic Analysis of Early-Responsive Redox-Sensitive Proteins in Arabidopsis. J. Proteom Res., 11: 412-424

11. Wang H, Liang Q, Cao K, Ge X*. (2011) Endogenous protein mono-ADP-ribosylation in Arabidopsis thaliana. Planta, 233:1287-1292

12. Wu Y, He Y, Ge X*. (2011) Functional characterization of the recombinant antimicrobial peptide Trx-Ace-AMP1 and its application on the control of tomato early blight disease. Appl. Microbiol. Biotechnol., 90:1303-1310

13. Ge X, Chang F, Ma H. (2010) Signaling and transcriptional control of reproductive development in Arabidopsis. Curr. Biol., 20: 988-997

14. Ge X, Li G, Wang S, Zhu H, Zhu T, Wang X, Xia Y*. (2007) AtNUDT7, a negative regulator of basal immunity in arabidopsis, modulates two distinct defense response pathways and is involved in maintaining redox homeostasis. Plant Physiol., 145: 204-215

15. Ge X, Dietrich C, Matsuno M, Li G, Berg H, Xia Y*. (2005) An Arabidopsis aspartic protease functions as an anti-cell-death component in reproduction and embryogenesis. EMBO Rep., 6(3):283-288