常芳

发布时间:2021-06-27浏览次数:14139

教师基本信息

职称:教授/博士生导师

电话:021-31246536

地址:复旦大学生命科学学院E401-8

电子邮件: fangchang@fudan.edu.cn

个人简介

常芳,复旦大学生命科学学院教授,博士生导师。教育部“双带头人”。2009 年博士毕业于中国农业大学;2009-2017年,复旦大学生命科学学院讲师、副教授/博导;2018年至今,复旦大学生命科学学院教授/博导。国家自然科学基金委优秀青年科学基金项目获得者,中国植物生理学会卫志明青年创新奖获得者。研究成果发表于The Plant CellNature CommunicationsMolecular Plant等国际前沿学术期刊。

研究方向

植物生殖发育与抗逆、植物合成生物学

综合利用分子遗传、细胞、生化、单细胞、合成生物学、及多维组学等方法,重点开展以下几方面的研究

1)植物生殖干细胞的命运决定和雄性不育;

2)全球气候变化下的生长和育性维持;

3)植物底盘系统的建立和合成生物学。

代表性成果(仅列第一或通讯作者)

[教材/专著]

Chang F, Wang Y, Ma H (eds.), Regulation of Plant Development. Singapore: Springer, 2026. (BOOK, ISBN 978-981-95-7032-4.)

[科研论文]

  1. Wang J, Zhou X, Sun W, Liu Y, Zhang S, Li H, Zhao Y, Xie X, Lei Z, Ma H, Chang F*(2026).Cryptic Fate Priming and Lineage Stabilization during Arabidopsis Anther Development, The Plant Cell, koag262, https://doi.org/10.1093/plcell/koag262.

  2. Lai Z‡, Lei Z‡, Wang J‡, Liu Y, Fu Y, Chang F* (2026). A PP2A Phosphatase-Defined Transcriptional Activity Window Safeguard Male Fertility, The Plant Cell, koag242, https://doi.org/10.1093/plcell/koag242.

  3. Sun W‡, Wang S‡, Ruan L, Hu L, Liu C, Feng Z, Ma H, Chang F* (2026). BAM3 Is a CLE19 Receptor that Mediates a Distinct Signaling Branch Controling Tapetum Degeneration and Polen Wall Formation. Plant Physiology, kiag599, https://doi.org/10.1093/plphys/kiag599.

  4. Chang F, Ma H (2026). Stamen and Anther Development. In: Chang F, Wang Y, Ma, H (eds) Regulation of Plant Development. Springer, Singapore. https://doi.org/10.1007/978-981-95-7033-1_9.

  5. Liu Y, Li M, Ma H, Chang F* (2026). Advances and perspectives in the regulation of anther development (in Chinese). Sci Sin Vitae, 2026, 56: 934-949.

  6. Wang S#, Zhang S#, Yu Y#, Wang JZ, Wang JY, Li M, Lu J, Ye J, Li H, Liu Y, Zhao Y, Song W, Dong J, Li J, Liu C, Ma H, Chang F* (2025). CLE19 Suppresses Brassinosteroid Signaling Output via the BSL-BIN2 Module to Maintain BES1 Activity and Pollen Exine Patterning in Arabidopsis. JIPB, 67:3216-3230. cover paper

  7. Yu Y#, Zhang S#, Chang F* (2025). CLE peptides: key regulators of plant development and stress adaption. Seed Biol 4: e009.

  8. Wang J, Lai Z, Lei Z,Chang F* (2026). Comprehensive Analysis of RNA Expression and Isoform Diversity Reveals Molecular Mechanisms in Plant Responses to Diverse Thermal Conditions. Phenomics, DOI: 10.1007/s43657-025-00254-5 

  9. Lai Z, Wang J, Fu Y, Wang M, Ma H, Peng S-Q, Chang F* (2024). Revealing the role of CCoAOMT1: fine-tuning bHLH transcription factors for optimal anther development. Sci China Life Sci, 67(3):565-578.

  10. Yu, Y#, Song, W#, Zhai, N#, Zhang S, Wang J, Wang S, Liu W, Huang CH, Ma H, Chai J, Chang F*(2023) PXL1 and SERKs act as receptor–coreceptor complexes for the CLE19 peptide to regulate pollen development. Nat Commun 14, 3307.

  11. Fu Y., Li M, Zhang S, Yang Q, Zhu E, You C, Qi J, Ma H*Chang F* (2020) Analyses of functional conservation and divergence reveals requirement of bHLH010/089/091 for pollen development at elevated temperature in Arabidopsis. JGG47:477-492.cover paper

  12. Lu J#, Fu Y#, Li M, Wang S, Wang J, Yang J, Ye J, Zhang X, Ma H*Chang F* (2020) Global Quantitative Proteomics Studies Revealed Tissue-Preferential Expression and Phosphorylation of Regulatory Proteins in Arabidopsis. Int. J. Mol. Sci. 21, 6116.

  13. Wang S, Lu J, Song X-F, Ren S-C, You C, Xu J, Liu C-M, Ma H, Chang F*(2017) Cytological and Transcriptomic Evidence Reveal Important Roles of CLE19 in Pollen Exine Formation. Plant Physiol. 175:1186-1202.

  14. Chang F, Cui J, Wang L, Ma H* (2017) The BIF Domain is Structurally and Functionally Distinct from Other Types of ACT-like Domains. Plant Cell, 29:1803-1805.

  15. Zhang S-S, Yang H, Ding L, Song Z-T, Ma H, Chang F*, Liu J-X* (2017) Tissue-Specific Transcriptomics Reveals an Important Role of the Unfolded Protein Response in Maintaining Fertility upon Heat Stress in Arabidopsis. Plant Cell, 29:1007-1023.

  16. Cui J, You C, Zhu E, Huang Q, Ma H*, Chang F*(2016) Feedback Regulation of DYT1 by Interactions with Downstream bHLH Factors Promotes DYT1 Nuclear Localization and Anther Development. Plant Cell, 28:1078-1093. highlighted paper

  17. Zhu E#, You C#, Wang S, Cui J, Niu B, Wang Y, Qi J, Ma H*, Chang F* (2015) The DYT1-interacting proteins bHLH010, bHLH089, and bHLH091 are redundantly required for Arabidopsis anther development and transcriptome. Plant J. 83:976-990.

  18. Yang H#, Chang F#,*, You C, Cui J, Zhu G, L., Zheng Y, Qi J*, Ma H* (2015) Whole genome DNA methylation patterns and complex associations with gene structure and expression during flower development in Arabidopsis.Plant J, 81: 268-281.

  19. Chang F, Zhang Z, Jin Y, Ma H* (2014) Cell biological analyses of anther morphogenesis and pollen viability in Arabidopsis and rice. Methods Mol Biol,1110:203-16.

  20. Chang F#, Gu Y#, Ma H, Yang Z* (2013) AtPRK2 promotes ROP1 activation via phosphorylation of RopGEFs to control polarized pollen tube growth. Mol Plant,6:1187-1201.

  21. Chang F#, Wang Y#, Wang S, Ma H* (2011) Molecular control of microsporogenesis in Arabidopsis. Curr Opin Plant Biol,14:66-73.