职称：青年副研究员
电子邮箱：anyanpeng2007@fudan.edu.cn
办公地点：生科楼D109
办公电话：021-31246731
研究方向
1、代谢性疾病的代谢组学研究
2、发展代谢组学数据分析新方法
个人简介
1.2002-2006年，山东大学生命科学学院，获生物科学学士学位；
2.2007-2013年，中国科学院武汉物理与数学研究所，获分析化学博士学位；
3.2013-2016年，复旦大学生命科学学院，生物学博士后；
4.2016年-至今，复旦大学生命科学学院，青年副研究员。目前负责代谢组学平台的日常运行。
曾主持1项国家自然科学基金委项目,参与5项国家重点研发计划和上海市科委项目。
代表性论文和论著
Yanpeng An#, Si Liu#, Fuhua Hao, Yulan Wang, Huiru Tang*,Development and validation of an improved probabilistic quotient normalization method for LC/MS- and NMR-based metabonomic analysis, Chinese Chemical Letters, 2020, 31(7): 1827-1830. (#Co-first author)
Zihan Ran#, Yanpeng An#, Ji Zhou, Jingmin Yang, Youyi Zhang, Jincheng Yang, Lei Wang, Xin Li, Daru Lu, Jing Zhong, Huaidong Song, Xingjun Qin, Rui Li*, Subchronic exposure to concentrated ambient PM2.5 perturbs gut and lung microbiota as well as metabolic profiles in mice, Environmental pollution (Barking, Essex : 1987), 2020, 272: 115987. (#Co-first author)
Hong Lin#, Yanpeng An#, Fuhua Hao, Yulan Wang, Huiru Tang*, Correlations of fecal metabonomic and microbiomic changes induced by high-fat diet in the pre-obesity state, Scientific Reports, 2016, 6, 21618. (#Co-first author)
Yangfang Ye#, Yanpeng An#, Ronghua Li, Changkao Mu, Chunlin Wang*, Strategy of metabolic phenotype modulation in portunus trituberculatus exposed to low salinity, Journal of Agricultural and Food Chemistry, 2014, 62(15): 3496-3503. (#Co-first author)
Yanpeng An, Wenxin Xu, Huihui Li, Heihua Lei, Limin Zhang, Fuhua Hao, Yixuan Duan, Xing Yan, Ying Zhao，Wujunfang，Yulan Wang, Huiru Tang*, High-fat diet induces dynamic metabolic alterations in multiple biological matrices of rats, Journal of Proteome Research, 2013,12(8): 3755-3768. (#Co-first author)
Jiali Zuo#，Runxian Cai#，Yanpeng An，Huiru Tang*, Simultaneous quantification of five stereoisomeric hexoses in nine biological matrices using ultrahigh performance liquid chromatography with tandem mass spectrometry, Journal of Analysis and Testing, 2020,4(4): 249-256. (#Co-first author)
Yufan Zheng#, Baiping Cui#, Wenrui Sun#, Sining Wang, Xu Huang, Han Gao, Fei Gao, Qian Cheng, Limin Lu, Yanpeng An, Xiaobo Li*, Ning Sun*, Potential crosstalk between liver and extra-liver organs in mouse models of acute liver injury, International Journal of Biological Sciences, 2020, 16(7): 1166-1179. (#Co-first author)
Ying Wang#，Chao Yin，Zhidan Chen，Yang Li，Yan Zou，Xiang Wang，Yanpeng An，Feizhen Wu，Guoping Zhang，Chunjie Yang，Huiru Tang，Yunzeng Zou*，Hui Gong*, Cardiac-specific LRP6 knockout induces lipid accumulation through Drp1/CPT1b pathway in adult mice, Cell and Tissue Research, 2020, 380(1): 143-153. (#Co-first author)
Yunlong Wang#, Xiangyu Wu#，Yanpeng An，Hui Xie，Fuhua Hao，Huiru Tang*, Quantitative metabonomic phenotypes in different structures of mung bean (Vigna radiata) seeds and their germination-associated dynamic changes, Journal of Proteome Research, 2020, 19(8): 3352-3363. (#Co-first author)
Yanfeng Jiang#, Kexun Zhang#, Zhen Zhu, Mei Cui, Yanpeng An, Yingzhe Wang, Chen Suo, Min Fan, Li Jin, Weizhong Tian*, Xingdong Chen*, Associations between serum metabolites and subclinical atherosclerosis in a Chinese population: the Taizhou Imaging Study, Aging-Us, 2020, 12(15): 15302-15313. (#Co-first author)
Mei Cui#，Yanfeng Jiang#，Qianhua Zhao，Zhen Zhu，Xiaoniu Liang，Kexun Zhang，WanqingWu，Qiang Dong，Yanpeng An, Huiru Tang，Ding Ding*，Xingdong Chen*, Metabolomics and incident dementia in older chinese adults: the shanghai aging study, Alzheimer's & dementia : the journal of the Alzheimer's Association, 2020, 16(5): 779-788. (#Co-first author)
Yan-Mei Chen#, Yuanting Zheng#, Ying Yu#, Yunzhi Wang#, Qingxia Huang#, Feng Qian#, Lei Sun#, Zhi-Gang Song, Ziyin Chen, Jinwen Feng, Yanpeng An, Jingcheng Yang, Zhenqiang Su, Shanyue Sun, Fahui Dai, Qinsheng Chen, Qinwei Lu, Pengcheng Li, Yun Ling, Zhong Yang, Huiru Tang, Leming Shi, Li Jin, Edward C. Holmes, Chen Ding*, Tong-Yu Zhu*, Yong-Zhen Zhang*, Blood molecular markers associated with COVID-19 immunopathology and multi-organ damage, The EMBO journal, 2020,39(24): e105896. (#Co-first author)
Ying Wang, Chao Yin, Zhidan Chen, Yang Li, Yan Zou, Xiang Wang, Yanpeng An, Feizhen Wu, Guoping Zhang, Chunjie Yang, Huiru Tang, Yunzeng Zou*, Hui Gong*, Cardiac-specific LRP6 knockout induces lipid accumulation through Drp1/CPT1b pathway in adult mice, Cell and tissue research, 2020, 380(1):143-153.
Hong Lin, Yanpeng An, Huiru Tang*, Yulan Wang*, Alterations of bile acids and gut microbiota in obesity induced by high fat diet in rat model, Journal of Agricultural and Food Chemistry, 2019, 67(13): 3624-3632.
Yanfeng Jiang, Zhen Zhu, Jie Shi, Yanpeng An, Kexun Zhang, Yingzhe Wang, Shuyuan Li, Li Jin, Weimin Ye, Mei Cui*, Xingdong Chen*, Metabolomics in the development and progression of dementia: a systematic review, Frontiers in Neuroscience, 2019, 13:343 .
Xiadi He, Wei Gong, Jianong Zhang, Ji Nie, Cuifang Yao, Fushen Guo, Yan Lin, Xiaohui Wu, Feng Li, Jie Li, Weicheng Sun, Enduo Wang, Yanpeng An, Huiru Tang, Guoquan Yan, Pengyuan Yang, Yun Wei, Yunzi Mao, Pengcheng Lin, Jianyuan Zhao, Yanhui Xu*, Wei Xu*, Shimin Zhao*, Sensing and transmitting intracellular amino acid signals through reversible lysine aminoacylations, Cell Metabolism, 2018, 27(1): 151-166.
Zhidan Chen#, Yang Li#, Ying Wang#, Juying Qian, Hong Ma, Xiang Wang, Guoliang Jiang, Ming Liu, Yanpeng An, Leilei Ma, Le Kang, Jianguo Jia, Chunjie Yang, Guoping Zhang, Ying Chen, Wei Gao, Mingqiang Fu, Zheyong Huang, Huiru. Tang, Yichun Zhu, Junbo Ge, Hui Gong*, Yunzeng Zou*, Cardiomyocyte-restricted low density lipoprotein receptor-related protein 6 (LRP6) deletion leads to lethal dilated cardiomyopathy partly through drp1 signaling, Theranostics, 2018, 8(3): 627-643. (#Co-first author)
Ning Li, Limin Zhang, Yanpeng An, Lulu Zhang, Yipeng Song, Yulan Wang, Huiru Tang*, Antagonist of prostaglandin E2 receptor 4 induces metabolic alterations in liver of mice, Journal of Proteome Research, 2015, 14(3): 1566-1573.
Huihui Li, Yanpeng An, Lulu Zhang, Hehua Lei, Limin Zhang, Yulan Wang, Huiru Tang*, Combined NMR and GC−MS analyses revealed dynamic metabolic changes associated with the carrageenan-induced rat pleurisy, Journal of Proteome Research, 2013, 12(12): 5520–5534.
Yixuan Duan, Yanpeng An, Ning Li, Bifeng Liu, Yulan Wang, Huiru Tang*, Multiple univariate data analysis reveals the inulin effects on the high-fat-diet induced metabolic alterations in rat myocardium and testicles in the pre-obesity state, Journal of Proteome Research, 2013, 12(7): 3480–3495.
Wenxin Xu, Junfang Wu, Yanpeng An, Chaoni Xiao, Fuhua Hao, Hongbing Liu, Yulan Wang, Huiru Tang*, Streptozotocin-induced dynamic metabonomic changes in rat biofluids, Journal of Proteome Research, 2012, 11(6): 3423-3435.
Limin Zhang, Yangfang Ye, Yanpeng An, Yuan Tian, Yulan Wang*, Huiru Tang*, Systems responses of rats to aflatoxin B1 exposure revealed with metabonomic changes in multiple biological matrices, Journal of Proteome Research, 2011, 10(2): 614-623.
Junfang Wu, Yanpeng An, Jianwu Yao, Yulan Wang, and Huiru Tang*, An optimised sample preparation method for NMR-based faecal metabonomic analysis, Analyst, 2010, 135(5): 1023-1030.