教师基本信息
职称：研究员
电子邮箱：chend@fudan.edu.cn
办公地点：复旦大学生命科学学院E301-2
办公电话：021-31246742
复旦大学特聘教授、复旦大学生命科学学院教授、遗传工程国家重点实验室PI、复旦大学附属中山医院双聘教授，博士生导师。2008年毕业于中国科学技术大学，细胞生物学博士；毕业后赴美国贝勒医学院从事生物质谱和蛋白质组学博士后研究工作；2012年全职回国在北京蛋白质组研究中心任副研究员、研究员；2015年加入复旦大学生命科学学院。目前担任复旦大学科技期刊发展中心主任，复旦大学人类表型组研究院副院长，中国生物物理学会表型组学分会创会秘书长，Springer出版集团《Phenomics》杂志创刊执行主编、国家十四五重点研发计划“生物大分子与微生物”首席科学家；入选国家级人才计划，北京市“海聚工程”特聘教授，北京市“优秀青年人才”，上海市“曙光人才计划”，上海市“优秀学术带头人计划”。近5年以通讯作者在Nat Biotechnol（2篇）、Nat Nanotechnol、Nat Biomed Eng、Cell Research、Gastroenterology、J Hematol Oncol（3篇）、Sci Transl Med、Nature Commun（21篇）、Cell Discov（2篇）、Adv Sci、Sci Adv、Hepatology、Genome Biol、Mol Cell、EMBO J、PNAS等国际高水平杂志发表论文70余篇，受邀撰写综述2篇，被引4000余次。主持国家科技部重点研发计划课题2项、科技部国际合作项目1项、863课题1项、国家自然科学基金重点项目3项、北京市自然科学基金1项、北京市留学人员重点项目1项，上海市市级重大科技专项1项，上海市张江专项2项，产学研项目1项；获得中国专利11项、美国专利1项。
研究方向
主要从事以蛋白质组为核心的临床多组学研究
Ø 开发一站式高效蛋白质组技术系统和数据云平台Firmiana。
Ø 建立了内源性转录因子活性分析技术（catTFRE）、转录因子DNA修饰结合偏好性解析技术（modi-TFRE）、染色质开放域转录调控蛋白质机器解析技术（ATAC-MS）。
Ø 利用多维度组学解析了脑部肿瘤（胶质瘤、垂体瘤、脊索瘤），消化道肿瘤（食管癌、胃癌、胃肠间质瘤、壶腹部肿瘤、胰腺癌、胆管癌、结直肠癌、结直肠早癌、十二指肠早癌），泌尿系统肿瘤（肾癌、膀胱癌），17个器官鳞癌，软组织肉瘤，黑色素瘤，乳腺癌各进展阶段，肺癌各进展阶段等多个世界或中国首项肿瘤人群多组学图谱，建立了完善的样本检测、数据处理、整合分析与可视化流程，明确了不同肿瘤的跨组学分子调控网络和肿瘤特异性驱动通路。
核心技术
Ø 一站式高效蛋白质组技术系统和数据云平台Firmiana（Nat Biotechnol，2017，2023）
Ø 内源性转录因子活性分析技术（catTFRE）（Nature Commun，2018，2019，2020）（发明专利3项）
Ø 转录因子DNA修饰结合偏好性解析技术（modi-TFRE）（Adv Sci，2021）
Ø 染色质开放域转录调控蛋白质机器解析技术（ATAC-MS）（Sci Adv，2021）
Ø 细胞和区域分辨率蛋白质组学解析技术（Cell Reports，2023）
招生专业
生物化学与分子生物学
获奖情况
2013年北京市第九批“海聚工程”
2014年北京市第七批“优秀青年人才”
2019年上海市“曙光人才”
2022年上海市“优秀学科带头人”
2022年国家级人才计划
2024年两项研究工作入选“中国2023年度重要医学进展”
代表性论文和论著
1. Zhang Q, Xu X, Jiang D, Wang Y, Wang H, Zhu J, Tang S, Wang R, Zhao S, Li K, Feng J, Xiang H, Yao Z, Xu N, Fang R, Guo W, Liu Y*, Hou Y*, Ding C*. Integrated proteogenomic characterization of ampullary adenocarcinoma. Cell Discov. 2025 Jan 7;11(1):2. doi: 10.1038/s41421-024-00742-4. PMID: 39762212; PMCID: PMC11704194.（Cell Discovery, IF=13.0）
2. Ran P, Wang Y, Li K, He S, Tan S, Lv J, Zhu J, Tang S, Feng J, Qin Z, Li Y, Huang L, Yin Y, Zhu L, Yang W*, Ding C*. STAVER: a standardized benchmark dataset-based algorithm for effective variation reduction in large-scale DIA-MS data. Brief Bioinform. 2024 Sep 23;25(6):bbae553. doi: 10.1093/bib/bbae553. PMID: 39504480; PMCID: PMC11540132.（Briefings In Bioinformatics, IF=6.8）
3. Xu G, Yu J, Lyu J, Zhan M, Xu J, Huang M, Zhao R, Li Y, Zhu J, Feng J, Tan S, Ran P, Su Z, Liu X, Zhao J, Zhang H*, Xu C*, Chang J*, Hou Y*, Ding C*. Proteogenomic Landscape of Breast Ductal Carcinoma Reveals Tumor Progression Characteristics and Therapeutic Targets. Adv Sci (Weinh). 2024 Oct 17:e2401041. doi: 10.1002/advs.202401041. Epub ahead of print. PMID: 39418072.（Advanced Science, IF=14.3）
4. Zhang Q, Xu Z, Han R, Wang Y, Ye Z, Zhu J, Cai Y, Zhang F, Zhao J, Yao B, Qin Z, Qiao N, Huang R, Feng J, Wang Y, Rui W, He F*, Zhao Y*, Ding C*. Proteogenomic characterization of skull-base chordoma. Nat Commun. 2024 Sep 27;15(1):8338. doi: 10.1038/s41467-024-52285-7. PMID: 39333076; PMCID: PMC11436687.（Nature Communication, IF=14.7）
5. Xiang H, Luo R, Wang Y, Yang B, Xu S, Huang W, Tang S, Fang R, Chen L, Zhu N, Yu Z, Akesu S, Wei C, Xu C*, Zhou Y*, Gu J*, Zhao J*, Hou Y*, Ding C*. Proteogenomic insights into the biology and treatment of pan-melanoma. Cell Discov. 2024 Jul 23;10(1):78. doi: 10.1038/s41421-024-00688-7. PMID: 39039072; PMCID: PMC11263678.（Cell Discovery, IF=13）
6. Li L, Jiang D, Liu H, Guo C, Zhang Q, Li X, Chen X, Chen Z, Feng J, Tan S, Huang W, Huang J, Xu C*, Liu CY*, Yu W*, Hou Y*, Ding C*. Comprehensive Proteogenomic Profiling Reveals the Molecular Characteristics of Colorectal Cancer at Distinct Stages of Progression. Cancer Res. 2024 Jun 11. doi: 10.1158/0008-5472.CAN-23-1878. Epub ahead of print. PMID: 38861363.（Cancer Research, IF=12.5）
7. Lyu J, Bai L, Li Y, Wang X, Xu Z, Ji T, Yang H, Song Z, Wang Z, Shang Y, Ren L, Li Y, Zang A, Jia Y*, Ding C*. Plasma proteome profiling reveals dynamic of cholesterol marker after dual blocker therapy. Nat Commun. 2024 May 8;15(1):3860. doi: 10.1038/s41467-024-47835-y. PMID: 38719824.（Nature Communication, IF=14.7）
8. Zhang P, Zhang W, Wang X, Li L, Lin Y, Wu N, Mao R, Lin J, Kang M*, Ding C*. BCLAF1 drives esophageal squamous cell carcinoma progression through regulation of YTHDF2-dependent SIX1 mRNA degradation. Cancer Lett. 2024 Apr 16;591:216874. doi: 10.1016/j.canlet.2024.216874. Epub ahead of print. PMID: 38636894.（Cancer Letters, IF=9.1）
9. Ma F, Li Y, Xiang C, Wang B, Lv J, Wei J, Qin Z, Pu Y, Li K, Teng H, Tan S, Feng J, Shang Z, Wang Y, Tian S, Du C*, Han Y*, Ding C*. Proteomic characterization of esophageal squamous cell carcinoma response to immunotherapy reveals potential therapeutic strategy and predictive biomarkers. J Hematol Oncol. 2024 Mar 15;17(1):11. doi: 10.1186/s13045-024-01534-9. PMID: 38491392; PMCID: PMC10943778.（Journal of Hematology & Oncology, IF=29.5）
10. Sun M, Tong Y, Yuan W, Wang Y, Pu Y, Huang W, Lv B, Xu C, Jiang W, Luo R, Fang R, Tang S, Ren L, Wang J, Feng J, Sun C, Shen K*, He F*, Hou Y*, Ding C*. Proteomic Characterization Identifies Clinically Relevant Subgroups of Gastrointestinal Stromal Tumors. Gastroenterology. 2024 Mar;166(3):450-465.e33. doi: 10.1053/j.gastro.2023.11.284. Epub 2023 Nov 22. PMID: 37995868.（Gastroenterology, IF=25.7）
11. Tang S, Wang Y, Luo R, Fang R, Liu Y, Xiang H, Ran P, Tong Y, Sun M, Tan S, Huang W, Huang J, Lv J, Xu N, Yao Z, Zhang Q, Xu Z, Yue X, Yu Z, Akesu S, Ding Y, Xu C*, Lu W*, Zhou Y*, Hou Y*, Ding C*. Proteomic characterization identifies clinically relevant subgroups of soft tissue sarcoma. Nat Commun. 2024 Feb 15;15(1):1381. doi: 10.1038/s41467-024-45306-y. PMID: 38360860; PMCID: PMC10869728.（Nature Communication, IF=14.7）
12. Li Y, Wang B, Yang W, Ma F, Zou J, Li K, Tan S, Feng J, Wang Y, Qin Z, Chen Z*, Ding C*. Longitudinal plasma proteome profiling reveals the diversity of biomarkers for diagnosis and cetuximab therapy response of colorectal cancer. Nat Commun. 2024 Feb 1;15(1):980. doi: 10.1038/s41467-024-44911-1. PMID: 38302471; PMCID: PMC10834432.（Nature Communication, IF=14.7）
13. Li Y, Wang B, Ma F, Jiang D, Wang Y, Li K, Tan S, Feng J, Wang Y, Qin Z, Xu G, Tian S, Zhang X, Xu C*, Wu J*, Xu J*, Hou Y*, Ding C*. Proteomic characterization of the colorectal cancer response to chemoradiation and targeted therapies reveals potential therapeutic strategies. Cell Rep Med. 2023 Dec 19;4(12):101311. doi: 10.1016/j.xcrm.2023.101311. Epub 2023 Dec 11. PMID: 38086380; PMCID: PMC10772406.（Cell Reports Medicine, IF=11.7）
14. Qu Y, Yao Z, Xu N, Shi G, Su J, Ye S, Chang K, Li K, Wang Y, Tan S, Pei X, Chen Y, Qin Z, Feng J, Lv J, Zhu J, Ma F, Tang S, Xu W, Tian X, Anwaier A, Tian S, Xu W, Wu X, Zhu S, Zhu Y, Cao D, Sun M, Gan H, Zhao J*, Zhang H*, Ye D*, Ding C*. Plasma proteomic profiling discovers molecular features associated with upper tract urothelial carcinoma. Cell Rep Med. 2023 Sep 19;4(9):101166. doi: 10.1016/j.xcrm.2023.101166. Epub 2023 Aug 25. PMID: 37633276; PMCID: PMC10518597.（Cell Reports Medicine, IF=11.7）
15. Yao Z, Xu N, Shang G, Wang H, Tao H, Wang Y, Qin Z, Tan S, Feng J, Zhu J, Ma F, Tian S, Zhang Q, Qu Y, Hou J*, Guo J*, Zhao J*, Hou Y*, Ding C*. Proteogenomics of different urothelial bladder cancer stages reveals distinct molecular features for papillary cancer and carcinoma in situ. Nat Commun. 2023 Sep 13;14(1):5670. doi: 10.1038/s41467-023-41139-3. PMID: 37704624; PMCID: PMC10499981.（Nature Communication, IF=14.7）
16. Zheng Y, Liu Y, Yang J, Dong L, Zhang R, Tian S, Yu Y, Ren L, Hou W, Zhu F, Mai Y, Han J, Zhang L, Jiang H, Lin L, Lou J, Li R, Lin J, Liu H, Kong Z, Wang D, Dai F, Bao D, Cao Z, Chen Q, Chen Q, Chen X, Gao Y, Jiang H, Li B, Li B, Li J, Liu R, Qing T, Shang E, Shang J, Sun S, Wang H, Wang X, Zhang N, Zhang P, Zhang R, Zhu S, Scherer A, Wang J, Wang J, Huo Y, Liu G, Cao C, Shao L, Xu J, Hong H, Xiao W, Liang X, Lu D, Jin L, Tong W, Ding C*, Li J*, Fang X*, Shi L*. Multi-omics data integration using ratio-based quantitative profiling with Quartet reference materials. Nat Biotechnol. 2024 Jul;42(7):1133-1149. doi: 10.1038/s41587-023-01934-1. Epub 2023 Sep 7. PMID: 37679543; PMCID: PMC11252085.（Nature Biotechnology, IF=33.1）
17. Tian S, Zhan D, Yu Y, Wang Y, Liu M, Tan S, Li Y, Song L, Qin Z, Li X, Liu Y, Li Y, Ji S, Wang S; Proteomic Massive Analysis and Quality Control Consortium; Zheng Y*, He F*, Qin J*, Ding C*. Quartet protein reference materials and datasets for multi-platform assessment of label-free proteomics. Genome Biol. 2023 Sep 7;24(1):202. doi: 10.1186/s13059-023-03048-y. PMID: 37674236; PMCID: PMC10483797.（Genome Biology, IF=10.1）
18. Wang L, Wan F, Xu Y, Xie S, Zhao T, Zhang F, Yang H, Zhu J, Gao J, Shi X, Wang C, Lu L, Yang Y, Yu X, Chen S, Sun X, Ding J, Chen P*, Ding C*, Xu F*, Yu H*, Peng H*. Hierarchical helical carbon nanotube fibre as a bone-integrating anterior cruciate ligament replacement. Nat Nanotechnol. 2023 Sep;18(9):1085-1093. doi: 10.1038/s41565-023-01394-3. Epub 2023 May 4. PMID: 37142709.（Nature Nanotechnology, IF=38.1）
19. Zhang H, Bai L, Wu XQ, Tian X, Feng J, Wu X, Shi GH, Pei X, Lyu J, Yang G, Liu Y, Xu W, Anwaier A, Zhu Y, Cao DL, Xu F, Wang Y, Gan HL, Sun MH, Zhao JY*, Qu Y*, Ye D*, Ding C*. Proteogenomics of clear cell renal cell carcinoma response to tyrosine kinase inhibitor. Nat Commun. 2023 Jul 17;14(1):4274. doi: 10.1038/s41467-023-39981-6. PMID: 37460463; PMCID: PMC10352361.（Nature Communication, IF=14.7）
20. Zhuang A, Zhuang A, Chen Y, Qin Z, Zhu D, Ren L, Wei Y, Zhou P, Yue X, He F*, Xu J*, Ding C*. Proteomic characteristics reveal the signatures and the risks of T1 colorectal cancer metastasis to lymph nodes. Elife. 2023 May 9;12:e82959. doi: 10.7554/eLife.82959. PMID: 37158593; PMCID: PMC10234629.（Elife, IF=6.4）
21. Li L, Jiang D, Liu H, Guo C, Zhao R, Zhang Q, Xu C, Qin Z, Feng J, Liu Y, Wang H, Chen W, Zhang X, Li B, Bai L, Tian S, Tan S, Yu Z, Chen L, Huang J, Zhao JY*, Hou Y*, Ding C*. Comprehensive proteogenomic characterization of early duodenal cancer reveals the carcinogenesis tracks of different subtypes. Nat Commun. 2023 Mar 29;14(1):1751. doi: 10.1038/s41467-023-37221-5. PMID: 36991000; PMCID: PMC10060430.（Nature Communication, IF=14.7）
22. Li L, Jiang D, Zhang Q, Liu H, Xu F, Guo C, Qin Z, Wang H, Feng J, Liu Y, Chen W, Zhang X, Bai L, Tian S, Tan S, Xu C, Song Q, Liu Y, Zhong Y, Chen T, Zhou P*, Zhao JY*, Hou Y*, Ding C*. Integrative proteogenomic characterization of early esophageal cancer. Nat Commun. 2023 Mar 25;14(1):1666. doi: 10.1038/s41467-023-37440-w. PMID: 36966136; PMCID: PMC10039899.（Nature Communication, IF=14.7）
23. Xiang H, Zhang B, Wang Y, Xu N, Zhang F, Luo R, Ji M*, Ding C*. Region-resolved multi-omics of the mouse eye. Cell Rep. 2023 Feb 28;42(2):112121. doi: 10.1016/j.celrep.2023.112121. Epub 2023 Feb 14. PMID: 36790928.（Cell Reports, IF=7.5）
24. Shi W, Wang Y, Xu C, Li Y, Ge S, Bai B, Zhang K, Wang Y, Zheng N, Wang J, Wang S, Ji G, Li J, Nie Y, Liang W, Wu X, Cui J, Wang Y, Chen L*, Zhao Q*, Shen L*, He F*, Qin J*, Ding C*. Multilevel proteomic analyses reveal molecular diversity between diffuse-type and intestinal-type gastric cancer. Nat Commun. 2023 Feb 14;14(1):835. doi: 10.1038/s41467-023-35797-6. PMID: 36788224; PMCID: PMC9929250.（Nature Communication, IF=14.7）
25. Deng M, Ran P, Chen L, Wang Y, Yu Z, Cai K, Feng J, Qin Z, Yin Y, Tan S, Liu Y, Xu C*, Shi G*, Ji Y*, Zhao JY*, Zhou J*, Fan J*, Hou Y*, Ding C*. Proteogenomic characterization of cholangiocarcinoma. Hepatology. 2023 Feb 1;77(2):411-429. doi: 10.1002/hep.32624. Epub 2022 Jul 5. PMID: 35716043; PMCID: PMC9869950.（Hepatology, IF=12.9）
26. Wang Y, Luo R, Zhang X, Xiang H, Yang B, Feng J, Deng M, Ran P, Sujie A, Zhang F, Zhu J, Tan S, Xie T, Chen P, Yu Z, Li Y, Jiang D, Zhang X*, Zhao JY*, Hou Y*, Ding C*. Proteogenomics of diffuse gliomas reveal molecular subtypes associated with specific therapeutic targets and immune-evasion mechanisms. Nat Commun. 2023 Jan 31;14(1):505. doi: 10.1038/s41467-023-36005-1. PMID: 36720864; PMCID: PMC9889805.（Nature Communication, IF=14.7）
27. Qu Y, Wu X, Anwaier A, Feng J, Xu W, Pei X, Zhu Y, Liu Y, Bai L, Yang G, Tian X, Su J, Shi GH, Cao DL, Xu F, Wang Y, Gan HL, Ni S, Sun MH, Zhao JY*, Zhang H*, Ye D*, Ding C*. Proteogenomic characterization of MiT family translocation renal cell carcinoma. Nat Commun. 2022 Dec 5;13(1):7494. doi: 10.1038/s41467-022-34460-w. PMID: 36470859; PMCID: PMC9722939.（Nature Communication, IF=14.7）
28. Zhang F, Zhang Q*, Zhu J, Yao B, Ma C, Qiao N, He S, Ye Z, Wang Y, Han R, Feng J, Wang Y, Qin Z, Ma Z, Li K, Zhang Y, Tian S, Chen Z, Tan S, Wu Y, Ran P, Wang Y, Ding C*, Zhao Y*. Integrated proteogenomic characterization across major histological types of pituitary neuroendocrine tumors. Cell Res. 2022 Dec;32(12):1047-1067. doi: 10.1038/s41422-022-00736-5. Epub 2022 Oct 28. PMID: 36307579; PMCID: PMC9715725.（Cell Research, IF=28.2）
29. Qie J, Liu Y, Wang Y, Zhang F, Qin Z, Tian S, Liu M, Li K, Shi W, Song L, Sun M, Tong Y, Hu P, Gong T, Wang X, Huang Y, Lin B, Zheng X, Zhou R, Lv J, Du C, Wang Y, Qin J, Yang W*, He F*, Ding C*. Integrated proteomic and transcriptomic landscape of macrophages in mouse tissues. Nat Commun. 2022 Nov 30;13(1):7389. doi: 10.1038/s41467-022-35095-7. PMID: 36450731; PMCID: PMC9712610.（Nature Communication, IF=14.7）
30. Tong Y, Sun M, Chen L, Wang Y, Li Y, Li L, Zhang X, Cai Y, Qie J, Pang Y, Xu Z, Zhao J, Zhang X, Liu Y, Tian S, Qin Z, Feng J, Zhang F, Zhu J, Xu Y, Lou W, Ji Y, Zhao J, He F*, Hou Y*, Ding C*. Proteogenomic insights into the biology and treatment of pancreatic ductal adenocarcinoma. J Hematol Oncol. 2022 Nov 25;15(1):168. doi: 10.1186/s13045-022-01384-3. PMID: 36434634; PMCID: PMC9701038.（Journal of Hematology & Oncology, IF=29.5）
31. Li Y, Xu C, Wang B, Xu F, Ma F, Qu Y, Jiang D, Li K, Feng J, Tian S, Wu X, Wang Y, Liu Y, Qin Z, Liu Y, Qin J, Song Q, Zhang X, Sujie A, Huang J, Liu T*, Shen K*, Zhao JY*, Hou Y*, Ding C*. Proteomic characterization of gastric cancer response to chemotherapy and targeted therapy reveals potential therapeutic strategies. Nat Commun. 2022 Nov 8;13(1):6749. doi: 10.1038/s41467-022-34238-0. Erratum for: Nat Commun. 2022 Sep 29;13(1):5723. PMID: 36347856; PMCID: PMC9643381.（Nature Communication, IF=14.7）
32. Xu N, Yao Z, Shang G, Ye D, Wang H, Zhang H, Qu Y, Xu F, Wang Y, Qin Z, Zhu J, Zhang F, Feng J, Tian S, Liu Y, Zhao J, Hou J, Guo J*, Hou Y*, Ding C*. Integrated proteogenomic characterization of urothelial carcinoma of the bladder. J Hematol Oncol. 2022 Jun 3;15(1):76. doi: 10.1186/s13045-022-01291-7. PMID: 35659036; PMCID: PMC9164575.（Journal of Hematology & Oncology, IF=29.5）
33. Qu Y, Feng J, Wu X, Bai L, Xu W, Zhu L, Liu Y, Xu F, Zhang X, Yang G, Lv J, Chen X, Shi GH, Wang HK, Cao DL, Xiang H, Li L, Tan S, Gan HL, Sun MH, Qiu J, Zhang H*, Zhao JY*, Ye D*, Ding C*. A proteogenomic analysis of clear cell renal cell carcinoma in a Chinese population. Nat Commun. 2022 Apr 19;13(1):2052. doi: 10.1038/s41467-022-29577-x. PMID: 35440542; PMCID: PMC9019091.（Nature Communication, IF=14.7）
34. Zhang H, Qin Z, Yue X, Liu Y, Sun X, Feng J, Xu Z, Zhao J, Li K, Qiu J, Yang W*, He F*, Ding C*. Proteome-wide profiling of transcriptional machinery on accessible chromatin with biotinylated transposons. Sci Adv. 2021 Oct 22;7(43):eabh1022. doi: 10.1126/sciadv.abh1022. Epub 2021 Oct 22. PMID: 34678055.（Science Advances, IF=11.7）
35. Bai L, Yang G, Qin Z, Lyu J, Wang Y, Feng J, Liu M, Gong T, Li X, Li Z, Li J, Qin J, Yang W*, Ding C*. Proteome-Wide Profiling of Readers for DNA Modification. Adv Sci (Weinh). 2021 Oct;8(19):e2101426. doi: 10.1002/advs.202101426. Epub 2021 Aug 5. PMID: 34351703; PMCID: PMC8498917.（Advanced Science, IF=14.3）
36. Wang Y, Song L, Liu M, Ge R, Zhou Q, Liu W, Li R, Qie J, Zhen B, Wang Y, He F*, Qin J*, Ding C*. A proteomics landscape of circadian clock in mouse liver. Nat Commun. 2018 Apr 19;9(1):1553. doi: 10.1038/s41467-018-03898-2. PMID: 29674717; PMCID: PMC5908788.（Nature Communication, IF=14.7）
37. Feng J, Ding C*, Qiu N, Ni X, Zhan D, Liu W, Xia X, Li P, Lu B, Zhao Q, Nie P, Song L, Zhou Q, Lai M, Guo G, Zhu W, Ren J, Shi T*, Qin J*. Firmiana: towards a one-stop proteomic cloud platform for data processing and analysis. Nat Biotechnol. 2017 May 9;35(5):409-412. doi: 10.1038/nbt.3825. PMID: 28486446.（Nature Biotechnology, IF=33.1）