Title：Hybrid Multicomposites for Biomedical Applications
Speaker：Adj. Prof. Dr. Hélder A. Santos(Faculty of Pharmacy, University of Helsinki,Helsinki, Finland)
时间：2015年6月28日（星期日） 14:00 ~ 16:00
地点：复旦大学江湾校区生命科学大楼B503室
Abstract：
The advent of novel engineering technologies affords unprecedented advances toward long-elusive objectives of medical research. Individualized medicine responds to the basic but generally unattainable question of identifying the right therapy, reaching the right therapeutic target in the body at the right time, and securing immediate feedback as for its efficacy and undesired collateral effect. Finally, individualized medicine appears to be a credible general objective in many pathologies, owing to the integration of classical disciplines of clinical medicine, methods of molecular biology, and novel engineered technological platforms. Nanotechnologies are of great interest in the context of the drive toward individualized medicine, and may prove to be the necessary catalyst for its large-scale implementation.
In this talk I will present different nanomaterials for the individualization of medical intervention: micro- and nano-particles are promising advanced drug delivery technologies for biomedical applications. Few examples will be given on the fabrication techniques of nanomaterials using advanced technologies, such as microfluidics; how they can be used to enhance the bioavailability of drug molecules, demonstrating their cytocompatibility and in vitro biodegradability and in vivo imaging and targeting potential. The recent cutting-edge advances on nanomaterials is anticipated to overcome some of the therapeutic window and clinical applicability of many drug molecules and can also act as innovative theranostic platform and tool for the clinic. The emergence of theranostic systems is expected to convey substantial benefits to the field of cancer therapy as it offers a less invasive alternative compared to the conventional therapeutic strategies and, thereby, enhancing the expectancy and quality of life of the patients.
Short Biography
Dr Hélder A. Santos is an Adjunct Professor in Pharmaceutical Nanotechnology, Head of the Research Unit Pharmaceutical Nanotechnology and Chemical Microsystems at the Division of Pharmaceutical Chemistry and Technology, an Academy Research Fellow, Principal Investigator, and an European Research Council Starting Grant grantee (2013–2017) at the Faculty of Pharmacy, University of Helsinki, Finland. Dr. Santos' research interests include the development of nanoparticles/nanomedicines for biomedical and healthcare applications. In 2010 he received the "Talent Prize in Science" attributed by the Portuguese government, and in 2013 and 2014 he received the Young Researcher Award 2013 and was distinguished by the exceptional scientific productivity, respectively, by the Faculty of Pharmacy at the University of Helsinki. Dr. Santos is the Editor for the Mesoporous Biomaterials journal and the Editor of the book "Porous Silicon for Biomedical Applications". Dr. Santos’ research career and development portfolio since 2009 totals over 4.1 M€ in project funding.