教师基本信息：
姓名：郑媛婷
Yuanting Zheng
职称：副教授，博士研究生导师
Associate Professor, PhD supervisor
电子邮箱：zhengyuanting@fudan.edu.cn
办公地点：复旦大学生命科学学院D610室
办公电话：021-31246746
个人网页/课题组主页：https://life.fudan.edu.cn/67/3f/c28175a354111/page.htm
研究方向：
（1）多组学驱动的药物基因组与表型组研究：发现“药物”个性化反应标志物与“患者”亚型特异性治疗靶点，阐明药物个性化反应和疾病异质性的分子遗传学基础。
（2）多组学标准物质和标准参考数据研发：https://chinese-quartet.org/
个人简介：
复旦大学生命科学学院副教授、博士生导师，兼任国际组学大数据质量控制学会(MAQC)中国分会主席、全国生物表型标准化工作组委员兼副秘书长、全国生物计量技术委员会协调工作组成员、中国生物物理学会表型组学分会委员等。
累计发表SCI论文70余篇，SCI他引3400余次，h指数28，其中包括以通讯作者发表Nature Biotechnology、Genome Biology、Nature Cancer等论文多篇。共同主编《大数据与精准医学》一书。
2009年博士毕业于中国药科大学。2009年7月-2016年2月在复旦大学药学院担任讲师，2016年2月加入复旦大学生命科学学院人类遗传学与人类学系，2017年2月晋升副教授。2024年获得国家杰出青年基金支持。
Dr. Yuanting Zheng is an associate professor at the School of Life Sciences of Fudan University. She is the president of the China chapter of the international Massive Analysis and Quality Control (MAQC) Society. Her research focuses on reference materials for multiomics quality control, aiming to empower multiomics for discovery of biomarker and therapeutic targets. She has published over 60 peer-reviewed papers in genomics and clinical pharmacology, such as Nature Biotechnology, Genome Biology, and Nature Cancer.
Dr. Yuanting Zheng received her PhD in clinical pharmacology from China Pharmaceutical University (2019), and worked in School of Pharmacology (2019-2016) and School of Life Sciences (2016-now) of Fudan University.
授课情况：
主讲本科生专业课《大数据与精准医学》。
Big data and Precision Medicine
招生专业：
科学学位：生物学（遗传学）
Biology
工程学位：生物与医药（精准医学大数据）
Biology and medicine
科研项目：
1.科技部科技基础资源调查专项“人基因组测序标准参考数据建设”(2022FY101203)，主持，2022.10~2025.09。
Special Project for Technology Basic Resources “Construction of human genome and transcriptome standard reference data”, Organize, 2022.10~2025.09.
2.国家重点研发计划“战略性国际科技创新合作”重点专项“人类表型组学数据融合分析的质量控制技术研究”(2018YFE0201603)，主持，2019.08~2022.07。
National Key R&D Project of China“Quality control studies for data integration analysis of human phenomics”, Organize, 2019.08~2022.07
代表性论文和论著：
Yuanting Zheng#*, Yaqing Liu#, Jingcheng Yang#, Lianhua Dong#, Rui Zhang#, Sha Tian#, Ying Yu, Luyao Ren, Wanwan Hou, Feng Zhu, Yuanbang Mai, Jinxiong Han, Lijun Zhang, Hui Jiang, Ling Lin, Jingwei Lou, Ruiqiang Li, Jingchao Lin, Huafen Liu, Ziqing Kong, Depeng Wang, Fangping Dai, Ding Bao, Zehui Cao, Qiaochu Chen, Qingwang Chen, Xingdong Chen, Yuechen Gao, He Jiang, Bin Li, Bingying Li, Jingjing Li, Ruimei Liu, Tao Qing, Erfei Shang, Jun Shang, Shanyue Sun, Haiyan Wang, Xiaolin Wang, Naixin Zhang, Peipei Zhang, Ruolan Zhang, Sibo Zhu, Andreas Scherer, Jiucun Wang, Jing Wang, Yinbo Huo, Gang Liu, Chengming Cao, Li Shao, Joshua Xu, Huixiao Hong, Wenming Xiao, Xiaozhen Liang, Daru Lu, Li Jin, Weida Tong, Chen Ding*, Jinming Li*, Xiang Fang*, Leming Shi*. Multi-omics data integration using ratio-based quantitative profiling with Quartet reference materials. Nature Biotechnology 2023 Sep 7. doi: 10.1038/s41587-023-01934-1. Online ahead of print.
Ying Yu#, Wanwan Hou#, Yaqing Liu#, Haiyan Wang#, Lianhua Dong#, Yuanbang Mai, Qingwang Chen, Zhihui Li, Shanyue Sun, Jingcheng Yang, Zehui Cao, Peipei Zhang, Yi Zi, Ruimei Liu, Jian Gao, Naixin Zhang, Jingjing Li, Luyao Ren, He Jiang, Jun Shang, Sibo Zhu, Xiaolin Wang, Tao Qing, Ding Bao, Bingying Li, Bin Li, Chen Suo, Yan Pi, Xia Wang, Fangping Dai, Andreas Scherer, Pirkko Mattila, Jinxiong Han, Lijun Zhang, Hui Jiang, Danielle Thierry-Mieg, Jean Thierry-Mieg, Wenming Xiao, Huixiao Hong, Weida Tong, Jing Wang, Jinming Li, Xiang Fang, Li Jin, Joshua Xu*, Feng Qian*, Rui Zhang*, Leming Shi*, Yuanting Zheng*. Quartet RNA reference materials improve the quality of transcriptomic data through ratio-based profiling. Nature Biotechnology 2023 Sep 7. doi: 10.1038/s41587-023-01867-9. Online ahead of print.
Ying Yu#, Naixin Zhang#, Yuanbang Mai#, Luyao Ren#, Qiaochu Chen, Zehui Cao, Qingwang Chen, Yaqing Liu, Wanwan Hou, Jingcheng Yang, Huixiao Hong, Joshua Xu, Weida Tong, Lianhua Dong, Leming Shi*, Xiang Fang*, Yuanting Zheng*. Correcting batch effects in large-scale multiomics studies using a reference-material-based ratio method. Genome Biology 2023; 24(1): 201.
Jingcheng Yang#, Yaqing Liu#, Jun Shang#, Qiaochu Chen, Qingwang Chen, Luyao Ren, Naixin Zhang, Ying Yu, Zhihui Li, Yueqiang Song, Shengpeng Yang, Andreas Scherer, Weida Tong, Huixiao Hong, Wenming Xiao, Leming Shi*, Yuanting Zheng*. The Quartet Data Portal: integration of community-wide resources for multiomics quality control. Genome Biology 2023; 24(1): 245.
Luyao Ren#, Xiaoke Duan#, Lianghua Dong#, Rui Zhang#, Jingcheng Yang#, Yuechen Gao, Rongxue Peng, Wanwan Hou, Yaqing Liu, Jingjing Li, Ying Yu, Naixin Zhang, Jun Shang, Fan Liang, Depeng Wang, Hui Chen, Lele Sun, Lingtong Hao, The Quartet Project Team, Andreas Scherer, Jessica Nordlund, Wenming Xiao, Joshua Xu, Weida Tong, Xin Hu, Peng Jia, Kai Ye, Jinming Li, Li Jin, Huixiao Hong*, Jing Wang*, Shaohua Fan*, Xiang Fang*, Yuanting Zheng*, Leming Shi. Quartet DNA reference materials and datasets for comprehensively evaluating germline variants calling performance. Genome Biology 2023; 24(1): 270.
Sha Tian#, Dongdong Zhan#, Ying Yu#, Yunzhi Wang, Mingwei Liu, Subei Tan, Yan Li, Lei Song, Zhaoyu Qin, Xianju Li, Yang Liu, Yao Li, Shuhui Ji, Shanshan Wang; Proteomic Massive Analysis and Quality Control Consortium; Yuanting Zheng*, Fuchu He*, Jun Qin*, Chen Ding*. Quartet protein reference materials and datasets for multi-platform assessment of label-free proteomics. Genome Biology 2023; 24 (1): 202.
Yi-Zhou Jiang#*, Ding Ma#, Xi Jin#, Yi Xiao#, Ying Yu#, Jinxiu Shi#, Yi-Fan Zhou, Tong Fu, Cai-Jin Lin, Lei-Jie Dai, Cheng-Lin Liu, Shen Zhao, Guan-Hua Su, Wanwan Hou, Yaqing Liu, Qingwang Chen, Jingcheng Yang, Naixin Zhang, Wen-Juan Zhang, Wei Liu, Weigang Ge, Wen-Tao Yang, Chao You, Yajia Gu, Virginia Kaklamani, François Bertucci, Claire Verschraegen, Anneleen Daemen, Nakul M. Shah, Ting Wang, Tiannan Guo, Leming Shi, Charles M. Perou, Yuanting Zheng*, Wei Huang*, Zhi-Ming Shao*. Integrated molecular portraits of breast cancer reveal therapeutic targets. Nature Cancer 2023 Accepted in principle.
Jun Shang#, He Jiang#, Yue Zhao#, Jinglei Lai#, Leming Shi, Jingcheng Yang*, Haiquan Chen*, Yuanting Zheng*. Differences of molecular events driving pathological and radiological progression of lung adenocarcinoma. eBioMedicine 2023; 94: 104728.
Bohu Pan#, Luyao Ren#, Vitor Onuchic#, Meijian Guan#, Rebecca Kusko#, Steve Bruinsma, Len Trigg, Andreas Scherer, Baitang Ning, Chaoyang Zhang, Christine Glidewell-Kenney, Chunlin Xiao, Eric Donaldson, Fritz J Sedlazeck, Gary Schroth, Gokhan Yavas, Haiying Grunenwald, Haodong Chen, Heather Meinholz, Joe Meehan, Jing Wang, Jingcheng Yang, Jonathan Foox, Jun Shang, Kelci Miclaus, Lianhua Dong, Leming Shi, Marghoob Mohiyuddin, Mehdi Pirooznia, Ping Gong, Rooz Golshani, Russ Wolfinger, Samir Lababidi, Sayed Mohammad Ebrahim Sahraeian, Steve Sherry, Tao Han, Tao Chen, Tieliu Shi, Wanwan Hou, Weigong Ge, Wen Zou, Wenjing Guo, Wenjun Bao, Wenzhong Xiao, Xiaohui Fan, Yoichi Gondo, Ying Yu, Yongmei Zhao, Zhenqiang Su, Zhichao Liu, Weida Tong, Wenming Xiao, Justin M Zook*, Yuanting Zheng*, Huixiao Hong*. Assessing reproducibility of inherited variants detected with short-read whole genome sequencing. Genome Biology 2022; 23(1): 2.
Michael M. Khayat, Sayed Mohammad Ebrahim Sahraeian, Samantha Zarate, Andrew Carroll, Huixiao Hong, Bohu Pan, Leming Shi, Richard A. Gibbs, Marghoob Mohiyuddin, Yuanting Zheng*, Fritz J. Sedlazeck*. Hidden biases in germline structural variant detection. Genome Biology 2021; 22(1): 347.