教师基本信息：
姓名：于梦 Meng Yu
职称：助理教授A Assistant professor
职务：课题组长（PI），博士生导师
电子邮箱：meng_yu@fudan.edu.cn
办公地点：复旦大学江湾校区生命科学学院
研究方向：
研究聚焦于能量代谢的神经调控，尤其是在哺乳期。将利用小鼠模型及表型、单细胞测序、生物化学方法及神经环路追踪等多方法系统整合以进行科学研究，解析调控哺乳期代谢适应不同表型的神经元亚群；揭示新的分子机制；再结合临床产后体重滞留等研究以探讨肥胖等代谢紊乱疾病的治疗策略。
欢迎有志于从事上述研究的博士后、研究生及本科生加盟研究团队。
Our research mainly focuses onneuroendocrine modulation of metabolic homeostasis, especially during lactation. We will systematically integrate multiple approaches, including mouse model & phenotypes, single-cell sequencing, biochemistry and neural circuit tracing, to identify neuron subpopulations that regulate different metabolic adaptations during lactation, and to uncover new molecular mechanisms. Finally, we explore therapeutic strategies for metabolic disorders like obesity in combination with clinical studies.
Postdocs, graduate students, and undergraduates who are interested in the above mentioned research are very welcome to join our team.
个人简介：
2026年2月加入复旦大学生命科学学院任助理教授，独立PI，博士生导师；2018年至2025年，于美国贝勒医学院从事博士后研究；2018年，毕业于复旦大学获神经生物学博士。在Nature Metabolism，Science Advances，Cell Research等期刊发表多篇研究成果。入选国家和上海人才项目（2025）。
2026，Assistant professor A (PI) at Fudan University
2018-2025, Postdoc at Baylor College of Medicine
2012-2018, PhD at Fudan University
Publications in Nature Metabolism，Science Advances，Cell Research and others.
授课情况：
招生专业：神经生物学，生理学Neurobiology, Physiology
科研项目：
获奖情况：
代表性论文和论著：
1. Yu M, Feng B, Bean JC, Zhao Q, Yang Y, Liu H, et al. Suppression of hypothalamic oestrogenic signal sustains hyperprolactinemia and metabolic adaptation in lactating mice. Nature Metabolism. 2025;7(4):759-77. doi:10.1038/s42255-025-01268-z. PMID: 40211044.
2. Zhang N, Yu M, Zhao Q, Feng B, Deng Y, Bean JC, et al. Altered thermal preference by preoptic estrogen receptor alpha neurons in postpartum females. Mol Metab. 2025 doi: 10.1016/j.molmet.2025.102108. PMCID: 11849645.
3. Yu M, Yin N, Feng B, Gao P, Yu K, Liu H, Liu H, Li Y, Ginnard OZ, Conde KM, Wang M, Fang X, Tu L, Bean JC, Liu Q, Deng Y, Yang Y, Han J, Jossy SV, Burt ML, Wong HZ, Yang Y, Arenkiel BR, He Y, Guo S, Gourdy P, Arnal JF, Lenfant F, Wang Z, Wang C, He Y, Xu Y. Identification of an ionic mechanism for ERalpha-mediated rapid excitation in neurons. Science Advances. 2024;10(40): eadp0696. Epub 2024/10/02 22:18. doi: 10.1126/sciadv.adp0696. PubMed PMID: 39356770.
4. Liu H, Bean JC, Li Y, Yu M, Ginnard OZ, Conde KM, Wang M, Fang X, Liu H, Tu L, Yin N, Han J, Yang Y, Tong Q, Arenkiel BR, Wang C, He Y, Xu Y. Distinct basal forebrain-originated neural circuits promote homoeostatic feeding and suppress hedonic feeding in male mice. Nat Metab. 2024;6(9):1775-90. Epub 2024/08/08. doi: 10.1038/s42255-024-01099-4. PubMed PMID: 39112722.
5. Yu M, Fu Y, Liang Y, Song H, Yao Y, Wu P, Yao Y, Pan Y, Wen X, Ma L, Hexige S, Ding Y, Luo S, Lu B. Suppression of MAPK11 or HIPK3 reduces mutant Huntingtin levels in Huntington's disease models. Cell Research. 2017 Dec;27(12):1441-1465. doi: 10.1038/cr.2017.113. Epub 2017 Oct 13. PMID: 29151587.