李晋

发布时间:2021-07-12浏览次数:7181

教师基本信息:

姓名:李晋

职称:青年研究员

电子邮箱:Li_Jin_lifescience@fudan.edu.cn

办公地点:复旦大学江湾校区生科楼C523

研究方向:

代谢性疾病的机制和治疗

个人简介:

复旦大学青年研究员,博士生导师,入选国家青年人才项目,上海市优秀青年学术带头人,生物物理学会代谢生物学分会青年副秘书长。2008年获得山东大学医学院学士学位,2011 年获得香港大学李嘉诚医学院硕士学位,2016年获得奥地利科学院分子医学研究中心博士学位;2016-2018年在哈佛医学院 Beth Israel Deaconess Medical Center从事博士后阶段工作;2018 年至今任复旦大学生科院青年研究员。

授课情况:

发育与代谢(秋季学期)

发育生物学(秋季学期

AIBS(上)

招生专业:

细胞生物学

代表性论文和论著:

五篇代表性文章 (#,共同通讯作者)

  1. Jin Li, …, Stefan Kubicek. “Artemisinins Target GABA A Receptor Signaling and Impair α Cell Identity”. Cell 2017.

  2. Jin Li#, …, Evan D. Rosen#. “Neurotensin is an anti-thermogenic peptide produced by lymphatic endothelial cells”. Cell Metabolism 2021.

  3. Li Lin, …, Jin Li. “LINEAGE: Label-free identification of endogenous informative single-cell mitochondrial RNA mutation for lineage analysis”. PNAS 2022.

  4. Cenxi Liu, …, Jin Li. “Metabolitin regulates intestinal fat absorption via lymphatic endothelial cells derived neurotensin”. Journal of Hepatology 2023a.

  5. Wei Fu, Cenxi Liu, Jin Li. “Short-term activation of PERK alleviates the progression of nonalcoholic steatohepatitis in mice”. Journal of Hepatology 2023b.

其他文章#,共同通讯作者)

  1. Xi Zeng, Shaowei Jiang, Zhixing Zhong, Xiaoping Yang, Qiuyue Chen,Jin Li#, Zhi Zhu#, Jia Song#, and Chaoyong Yang#. “DIRECT: Digital Microfluidics for Isolation-Free Shared Library Construction of Single-Cell DNA Methylome and Transcriptome”. Small Methods 2023.

  2. Xinrui Lin, Yingwen Chen, Li Lin, Kun Yin, Rui Cheng, Xin Lin, Xiaoyu Wang, Ye Guo, Zhaorun Wu, Yingkun Zhang, Jin Li#, Chaoyong Yang#, Jia Song#. “mitoSplitter: A mitochondrial variants-based method for efficient demultiplexing of pooled single-cell RNA-seq”. PNAS 2023.

  3. Cenxi Liu, Xuelian Xiong#, Jin Li#. “Regulation of atherosclerosis development by neurotensin derived from lymphatic endothelial cells in mice”. ATVB 2023.

  4. Xiao Guo, …, Jin Li. “BCAA insufficiencies lead to premature ovarian insufficiency via ceramide induced elevation of ROS”. EMBO Molecular Medicine 2023.

  5. Cenxi Liu, Jin Li. “The physiological functions of lymphangiocrine signals”. Trends in Endocrinology and Metabolism 2023a. (Review)

  6. Wei Fu, Hongwei Jiang# and Jin Li#. “Artemether treatment improves islet function and metabolic homeostasis in diabetic non-human primates”. Journal of Diabetes 2023.

  7. Yufeng Zhang, Xinrui Lin and Jin Li. “The controversy about artemisinins’effects of on the islet cell reprogramming and diabetes”. Trends in Endocrinology and Metabolism 2023b. (Review)

  8. Ziyang Lu, …, Jin Li#. “Identification of clinical and molecular features for recurrent serous borderline ovarian tumor”. EClinicalMedicine 2022.

  9. Chuanyou Yi, …, Jin Li#.“The storage conditions of high fat diet are the key factors for diet induced obesity and liver damage”. Nutrients 2022.

  10. Dandan Li, …, Jin Li#, Shangyu Hong#. “Hepatocyte specific depletion of Nnmt protects the mice from non-alcoholic steatohepatitis”. Journal of Hepatology 2022.

  11. Jia Song, …, Jin Li#, Yanling Song#, Chaoyong Yang#. “ENtropy subspaces separation-based Clustering method for nOise REduction (ENCORE): a computational algorism for single cell RNA-seq data”. Nuclei Acids Research 2021.

  12. Tamara Casteels, …, Jin Li# and Stefan Kubicek#. “An inhibitor-mediated beta-cell dedifferentiation model reveals distinct roles for FoxO1 in glucagon repression and insulin maturation”. Molecular Metabolism 2021.

  13. Li Yang, …, Jin Li#, and Bing Zhao#. “Modeling hepatoblastoma development with human fetal liver organoids reveals YAP1 activation is sufficient for tumorigenesis”. Protein & Cell 2021.