余垚

发布时间:2021-07-12浏览次数:4178

教师基本信息

姓名:余垚

职称:副研究员

电子邮箱yaoyu@fudan.edu.cn

办公地点:生科院E501-2

办公电话021-31246578


研究方向

酵母分子遗传学,遗传工程,合成生物学


个人简介

2000获复旦大学微生物学学士学位,2006年,获复旦大学遗传学博士学位。2006-2011年在美国纽约州立大学石溪分校从事博士后研究。20117月任复旦大学生命科学学院副研究员。目前承担国家自然基金委面上项目。曾获第二届上海高校青年教师教学竞赛(自然科学基础学科)一等奖, 被评为上海市教学能手。


授课情况

改变生命的生物技术(全国一流本科课程)

遗传工程原理与应用


招生专业

遗传学


代表性论文和论著

1. Yu Y, Mo W, Ren H, Yang X, Lu W, Luo T, Zeng J, Zhou J, Qi J*, Lu H*. 2021. Comparative genomic and transcriptomic analysis reveals specific features of gene regulation in Kluyveromyces marxianus. Front Microbiol. doi: 10.3389/fmicb.2021.598060

2.Wu L, Wang M, Zha G, Zhou J, Yu Y#, Lu H#. 2020. Improving the expression of a heterologous protein by genome shuffling in Kluyveromyces marxianus. J Biotechnol 320:11-16.

3.Zhou J, Zhu P, Hu X, Lu H, Yu Y*. 2018. Improved secretory expression of lignocellulolytic enzymes in Kluyveromyces marxianus by promoter and signal sequence engineering. Biotechnol Biofuels 11:235.

5.Chen Y, Hu X, Guo C, Yu Y#, Lu H#. 2017. Epe1 contributes to activation of AMPK by promoting phosphorylation of AMPK alpha subunit, Ssp2. Sci Rep 7:3208.

6.Yu Y, Zhou H, Deng X, Wang W, Lu H. 2016. Set3 contributes to heterochromatin integrity by promoting transcription of subunits of Clr4-Rik1-Cul4 histone methyltransferase complex in fission yeast. Sci Rep 6:31752.

8.Zhou H, Liu Q, Shi T, Yu Y*, Lu H. 2015. Genome-wide screen of fission yeast mutants for sensitivity to 6-azauracil, an inhibitor of transcriptional elongation. Yeast 32:643-55.

11.Deng X, Zhou H, Zhang G, Wang W, Mao L, Zhou X, Yu Y#, Lu H#. 2015. Sgf73, a subunit of SAGA complex, is required for the assembly of RITS complex in fission yeast. Sci Rep 5:14707.

12.Lei B, Zhou N, Guo Y, Zhao W, Tan YW, Yu Y#, Lu H#. 2014. Septin ring assembly is regulated by Spt20, a structural subunit of the SAGA complex. J Cell Sci 127:4024-36.

14.Pan X, Lei B, Zhou N, Feng B, Yao W, Zhao X, Yu Y#, Lu H#. 2012. Identification of novel genes involved in DNA damage response by screening a genome-wide Schizosaccharomyces pombe deletion library. BMC Genomics 13:662.

15.Yu Y, Srinivasan M, Nakanishi S, Leatherwood J, Shilatifard A, Sternglanz R*. 2011. A conserved patch near the C terminus of histone H4 is required for genome stability in budding yeast. Mol Cell Biol 31:2311-25.

17.Li Y, Yu Y, Zhang Y, Zhou Y, Li C, Zhu J, Yuan H, Lu H*. 2011. MAFIP is a tumor suppressor in cervical cancer that inhibits activation of the nuclear factor-kappa B pathway. Cancer Sci 102:2043-50.

18.Yu Y, Neiman AM, Sternglanz R*. 2010. The JmjC domain of Gis1 is dispensable for transcriptional activation. FEMS Yeast Res 10:793-801.

19.Kumar PR, Yu Y, Sternglanz R, Johnston SA, Joshua-Tor L*. 2008. NADP regulates the yeast GAL induction system. Science 319:1090-2.